718630-59-2
718630-59-2
Chemical Structure
PHA-793887
- CAS No.: 718630-59-2
- Formula:C19H31N5O2
- Molecular Weight:361.48
IUPAC Name: N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide
InChIKey: HUXYBQXJVXOMKX-UHFFFAOYSA-N
SMILES: CC(C)CC(NC1=NNC2=C1CN(C(C3CCN(C)CC3)=O)C2(C)C)=O
Biological Activity: PHA-793887 is a potent, ATP-competitive CDK inhibitor, can inhibit Cdk2, Cdk1, Cdk4, and Cdk9 with IC50s of 8 nM, 60 nM, 62 nM and 138 nM, respectively, and also inhibits glycogen synthase kinase 3β with an IC50 of 79 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PHA-793887 | 99.25% | PHA-793887 is a potent, ATP-competitive CDK inhibitor, can inhibit Cdk2, Cdk1, Cdk4, and Cdk9 with IC50s of 8 nM, 60 nM, 62 nM and 138 nM, respectively, and also inhibits glycogen synthase kinase 3β with an IC50 of 79 nM. | ||||||||||||||||||||
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Keywords
