3 Results for "

PIM447

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PIM447" in MCE Product Catalog:

  • Targets Recommended:
8
8 Cited Publications
Cat. No.: HY-19322B
CAS No.: 1820565-69-2
Synonyms: LGH447 dihydrochloride
Target:  

Pim Apoptosis

Research Areas:  

Cancer

PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis .
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8
8 Cited Publications
Cat. No.: HY-19322
CAS No.: 1210608-43-7
Synonyms: LGH447
Target:  

Pim Apoptosis

Research Areas:  

Cancer

PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis .
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Cat. No.: HY-19322C
Synonyms: (1S,3R,5R)-LGH447 dihydrochloride
Target:  

Pim

Research Areas:  

Cancer

(1S,3R,5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.
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