4 Results for "

PRDM14

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "PRDM14" in MCE Product Catalog:

PRDM14 Human Pre-designed siRNA Set A
PRDM14 Human Pre-designed siRNA Set A
Cat. No.: HY-RS11064
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

PRDM14 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDM14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PRDM14 Antibody (YA4480)
PRDM14 Antibody (YA4480)
0 Images
Cat. No.: HY-P84783
Synonyms: PFM11

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

PRDM14 Antibody (YA4480)(PBS only)
PRDM14 Antibody (YA4480)(PBS only)
0 Images
Cat. No.: HY-P84783A
Synonyms: PFM11

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

Go 6983 (GMP)
Go 6983 (GMP)
0 Images
Cat. No.: HY-13689G
CAS No.: 133053-19-7
Go 6983 GMP is Go 6983 (HY-13689) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Go 6983 is a dual inhibitor targeting Suv39h1/2 (KMT1A/KMT1B) and PKC, as well as a transcriptional activator capable of inducing DNA hypomethylation. Go 6983 stimulates the transcription of Prdm14 by reducing Suv39h1/2 protein levels, decreasing histone modifications in the Prdm14 promoter region, and increasing the recruitment of RNA polymerase II. Go 6983 induces genome-wide DNA hypomethylation by inhibiting de novo methyltransferase expression and increasing Tet1/Tet2 levels, thereby promoting self-renewal and pluripotency maintenance of stem cells. Meanwhile, Go 6983 can block PKC-mediated signaling pathways to reduce the expression of EMT-related genes and eliminate the upregulation of antioxidant genes downstream of NRF2. Go 6983 is mainly used in mechanism studies related to myocardial ischemia/reperfusion injury .
Assay Types