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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
PRISM
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "PRISM" in MCE Product Catalog:
Synonyms: BRD5846
Target:
Research Areas:
BAY-888 is a selective CK1α/CSNK1A1 (casein kinase 1α) ATP-competitive inhibitor (IC50: 4 nM@10 μM ATP; 63 nM@1 mM ATP). BAY-888 blocks the negative regulation of p53 and other signaling pathways by CK1α, induces apoptosis and inhibits proliferation of tumor cells. BAY-888 has shown inhibitory efficacy against cancers such as acute myeloid leukemia (AML) in PRISM barcoded cell line screening and can mimic the effects of shRNA-mediated CK1α knockdown. BAY-888 is primarily used for the development of anticancer drugs for p53 wild-type tumors and for the study of the mechanisms of CK1α-related signaling pathways .
Cat. No.: HY-123610
CAS No.: 1456542-69-0
Target:
Research Areas:
BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively .
Cat. No.: HY-RS11070
Target:
Research Areas:
PRDM6 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDM6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704006
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: E3 ubiquitin-protein ligase pellino homolog 1; PELI1; PRISM
Cat. No.: HY-P75970
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: E3 ubiquitin-protein ligase pellino homolog 1; PELI1; PRISM
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
