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Results for "

PS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Akt (3) Amyloid-β (4) Antibiotic (2) Apoptosis (19) Aryl Hydrocarbon Receptor (3) Autophagy (7) Bacterial (5) Bcl-2 Family (2) BCRP (1) Biochemical Assay Reagents (16) c-Myc (1) Calcium Channel (1) Caspase (1) CDK (2) CHIKV (1) ClpP (1) COX (2) CXCR (2) Cytochrome P450 (2) DNA/RNA Synthesis (10) Dopamine Transporter (1) Drug Derivative (1) Endogenous Metabolite (5) Enterovirus (1) Environmental Pollutants (1) ERK (4) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (3) Exosomes (3) Ferroptosis (3) FGFR (1) Flavivirus (1) Fluorescent Dye (5) Fungal (2) Glutathione Peroxidase (2) GPR39 (1) Herbicide (1) HSP (3) IAP (1) IFNAR (1) IKK (3) Insulin Receptor (1) Integrin (1) Interleukin Related (2) Isotope-Labeled Compounds (16) LDLR (1) Liposome (11) LPL Receptor (1) LRRK2 (1) Mitochondrial Metabolism (1) Molecular Glues (2) Monoamine Oxidase (1) mTOR (10) NADPH Oxidase (2) NAMPT (1) NF-κB (5) Nucleoside Antimetabolite/Analog (1) OGA (1) Orthopoxvirus (1) p38 MAPK (3) PAK (1) PDHK (1) PDK-1 (5) Phosphoramidites (1) Photosensitizer (2) PI3K (4) Pim (1) PKC (3) PPAR (1) PROTACs (4) Proteasome (6) Pyroptosis (1) Ras (5) Reactive Oxygen Species (ROS) (7) Reference Standards (7) SARS-CoV (1) Sirtuin (2) Small Interfering RNA (siRNA) (1) SOS1 (4) STAT (1) STING (3) Survivin (1) Tau Protein (1) Thrombin (1) TNF Receptor (3) TREM receptor (4) TRP Channel (1) VD/VDR (1) VEGFR (1) γ-secretase (4)
By Research Areas:	Cancer (61) Cardiovascular Disease (3) Infection (6) Inflammation/Immunology (23) Metabolic Disease (18) Neurological Disease (24)
Oligonucleotides:	Nucleoside Analogs (1) Phospholipids (9) Human Pre-designed siRNA Sets (1) Cap Analogs (2) Uracil (1) Phosphoramidites (1) Antisense Oligonucleotides (4) Cytidine (1) siRNAs (1)

162

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10227

Bortezomib Maximum Cited Publications 248 Publications Verification PS-341; LDP-341; NSC 681239	Proteasome NF-κB Apoptosis Autophagy TREM receptor	Cancer
Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .

HY-12885

2’3’-c-di-AM(PS)2 (Rp,Rp) 85+ Cited Publications ADU-S100; MIW815; ML RR-S2 CDA	STING	Inflammation/Immunology Cancer
2’3’-c-di-AM(PS)2 (Rp,Rp) (ADU-S100), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity .

HY-12885A

2’3’-c-di-AM(PS)2 (Rp,Rp) disodium salt 85+ Cited Publications ADU-S100 disodium salt; MIW815 disodium salt; ML RR-S2 CDA disodium salt	STING	Inflammation/Immunology Cancer
2’3’-c-di-AM(PS)2 (Rp,Rp) disodium salt (ADU-S100 disodium salt) is an activator of stimulator of interferon genes (STING).

HY-12885B

2’3’-c-di-AM(PS)2 (Rp,Rp) ammonium salt 85+ Cited Publications ADU-S100 ammonium salt; MIW815 ammonium salt; ML RR-S2 CDA ammonium salt	STING	Inflammation/Immunology Cancer
2’3’-c-di-AM(PS)2 (Rp,Rp) ammonium salt (ADU-S100 ammonium salt), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity .

HY-18008

PS-1145 4 Publications Verification	IKK Apoptosis	Cancer
PS-1145 is an IκB kinase (IKK) inhibitor with an IC₅₀ of 88 nM.

HY-15967

PS48 5 Publications Verification	PDK-1	Cancer
PS48 is an activator of PDK1 with an AC₅₀ of 8 μM.

HY-121744

PS10 5+ Cited Publications	PDHK	Inflammation/Immunology
PS10 is a novel, potent and ATP-competitive pan-PDK inhibitor, inhibits all PDK isoforms with IC₅₀ of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively. PS10 shows high affinity for PDK2 (K_d= 239 nM) than for Hsp90 (K_d= 47 μM) . PS10 improves glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity. PS10 has the potential for the investigation of diabetic cardiomyopathy .PDK: pyruvate dehydrogenase kinase

HY-126213

1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium 18:1 Lyso-PS	NADPH Oxidase Interleukin Related Apoptosis	Inflammation/Immunology
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following NADPH oxidase activation and Lyso-PS signal transduction. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium signals through macrophage G2A to enhance the phagocytic uptake of PS-dependent apoptotic (apoptosis) neutrophils and PS-exposed activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium enhances macrophage phagocytic uptake of apoptotic cells, carboxylate-modified microspheres, and PS-exposed non-apoptotic activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium serves as an acyl acceptor substrate for the lysophosphatidyltransferase At1g78690p to generate diacylphosphatidylserine. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium reduces the secretion of IL-8 and decreases the proportion of viable colon cancer cells. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium is applicable to studies on peritonitis and inflammatory bowel disease .

HY-121629

PS210	PDK-1	Cancer
PS210 is a potent and selective PDK1 activator with a K_d of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K .

HY-111149A

PS372424 hydrochloride 2 Publications Verification	CXCR	Inflammation/Immunology
PS372424 hydrochloride, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 hydrochloride prevents human T-cell migration in a humanized model of arthritic inflammation .

HY-10227R

Bortezomib (Standard) PS-341 (Standard); LDP-341 (Standard); NSC 681239 (Standard)	Reference Standards Proteasome NF-κB Apoptosis Autophagy TREM receptor	Cancer
Bortezomib (Standard) is the analytical standard of Bortezomib. This product is intended for research and analytical applications. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .

HY-162919

YK-2168	CDK Apoptosis c-Myc	Cancer
YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. YK-2168 inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. YK-2168 induces apoptosis in tumor cells, suppresses expression of CDK9-regulated genes including MYC and Mcl1, and inhibits tumor growth in CDX mice models. YK-2168 can be used for the research of cancer, such as leukemia .

HY-103053

PS121912	VD/VDR Apoptosis	Cancer
PS121912 is a selective vitamin D receptor (VDR)-coregulator inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer .

HY-145539

1,2-Dipalmitoyl-sn-glycero-3-PS sodium	Liposome	Others
1,2-Dipalmitoyl-sn-glycero-3-PS sodium is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is used for the preparation of phospholipid bilayers .

HY-148978

18:0,18:1 PS sodium	Exosomes Endogenous Metabolite Liposome	Metabolic Disease
18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-W714524

1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium 16:0-18:1 PS (POPS)	Liposome	Others
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium (16:0-18:1 PS (POPS)) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes .

HY-117366

PS432	PKC	Cancer
PS432 is a PKC inhibitor with IC₅₀s of 16.9 μM (PKC_ι) and 18.5 μM (PKC_ζ), respectively. PS432 effectively inhibits the proliferation of non-small cell lung cancer cells (NSCLCs) and tumor growth in mouse xenograft models .

HY-12885C

2’3’-c-di-AM(PS)2 (Rp,Rp) enantiomer ammonium salt ADU-S100 enantiomer ammonium salt; MIW815 enantiomer ammonium salt; ML RR-S2 CDA enantiomer ammonium salt	IFNAR	Inflammation/Immunology
2’3’-c-di-AM(PS)2 (Rp,Rp) enantiomer ammonium salt (ADU-S100 enantiomer ammonium salt) is the less active enantiomer of 2’3’-c-di-AM(PS)2 (Rp,Rp). 2’3’-c-di-AM(PS)2 (Rp,Rp) is an activator of stimulator of interferon genes (STING) .

HY-107412

Proteasome inhibitor IX PS-IX; AM114	Proteasome	Cancer
Proteasome inhibitor IX (PS-IX; AM114) is a Chalcone derivative and a chymotrypsin-like activity of the 20S proteasome inhibitor with an IC₅₀ value of ~1 μM. Proteasome inhibitor IX exhibits HCT116 p53 ^+/+ cells growth inhibitory activity with an IC₅₀ value of 1.49 μM. Proteasome inhibitor IX has potent anticancer activity .

HY-10227S

Bortezomib-d8 PS-341-d₈; LDP-341-d₈; NSC 681239-d₈	Isotope-Labeled Compounds Proteasome NF-κB Apoptosis Autophagy TREM receptor	Cancer
Bortezomib-d₈ is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .

HY-B1731

Phenyl salicylate	Bacterial	Neurological Disease
Phenyl salicylate (PS) has antibacterial activity when hydrolyzed in small intestine and is often used as nervous system inhibitor and intestinal preservative .

HY-13851

PS47	PDK-1	Others
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48 .

HY-P990144

Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2)	Integrin	Inflammation/Immunology Cancer
Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) is an anti-mouse/human VLA-4/CD49d IgG2b monoclonal antibody. Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) can reduce VLA-4 positive cells. Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) can inhibit the migration of Tc1 cells to tumors. Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) inhibits the retention of leukemia cells in the spleen and bone marrow by blocking VLA-4. Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) can be used for research on inflammation conditions and cancer such as experimental autoimmune encephalomyelitis (EAE), melanoma and leukemia .

HY-165084

L-a-Phosphatidylserine sodium Soy PS sodium	Liposome	Inflammation/Immunology
L-a-Phosphatidylserine sodium is an antigen targeting phosphatidylserine (PS) and can induce the production of polyclonal antibodies. L-a-Phosphatidylserine can trigger complement-dependent immune damage by binding to PS on the cell membrane surface. After L-a-Phosphatidylserine is recognized by antibodies, it activates the complement system, causing liposome membrane damage and content release, and then participates in the regulation of immune response and cell apoptosis signaling. L-a-Phosphatidylserine can be used in immunological research, such as antibody specificity analysis and complement activation mechanism research .

HY-157623

16:0 Lyso PS 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium	Biochemical Assay Reagents	Others
16:0 Lyso PS (1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium) is a lysophospholipid. 16:0 Lyso PS serves as a standard for preparing standard curves .

HY-N0409

Picroside III 1 Publications Verification	Others	Inflammation/Immunology
Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-111149

PS372424	CXCR	Inflammation/Immunology
PS372424, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 prevents human T-cell migration in a humanized model of arthritic inflammation .

HY-13856

(R)-PS210	PDK-1	Cancer
(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC₅₀ value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of?PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment .

HY-D2418

PS-SCOTfluor-12	Fluorescent Dye	Metabolic Disease
PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .

HY-50882

ELN318463	γ-secretase	Neurological Disease
ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC₅₀s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is 51-fold more selective for PS1 .

HY-163445

NAMPT activator-6	NAMPT	Cancer
NAMPT activator-6 is a NAMPT activator, a regulatory molecule for the optical control system of NAMPT and NAD+. NAMPT activator-6 can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) to achieve up-down reversible regulation of NAMPT and NAD+ in a light-dependent manner and reduce the toxicity associated with inhibitor-based PS-PROTACs. PS-PROTAC can be used to achieve antitumor activity, NAMPT, and NAD+ modulation in vivo via optical manipulation .

HY-139973

OAB-14	Amyloid-β	Neurological Disease
OAB-14, is a Bexarotene (HY-14171) derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal pathway in APP/PS1 transgenic mice .

HY-146885S

16:0-18:1 PS-d31 sodium 1 Publications Verification	Isotope-Labeled Compounds	Others
16:0-18:1 PS-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PS (sodium).

HY-148977

18:0,22:6 PS sodium	Endogenous Metabolite	Metabolic Disease
18:0,22:6 PS sodium is a lipid component of synaptic vesicles and cholesterol, which can be used for metabolic research .

HY-10227G

Bortezomib PS-341; LDP-341; NSC 681239	Proteasome NF-κB Apoptosis Autophagy TREM receptor	Cancer
Bortezomib (GMP) (PS-341 (GMP)) is Bortezomib (HY-10227) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .

HY-172378

Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000)	Biochemical Assay Reagents	Others
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .

HY-157692

10:0 PS 1,2-Didecanoyl-sn-glycero-3-phospho-L-serine sodium	Biochemical Assay Reagents
10:0 PS (1,2-Didecanoyl-sn-glycero-3-phospho-L-serine (sodium)) is a kind of biochemical reagent.

HY-170670

DQ661	Autophagy mTOR	Cancer
DQ661 is a potent PPT1 inhibitor. DQ661 is a dimeric quinacrine autophagy inhibitor. DQ661 inhibits mTORC1 activity. DQ661 decreases the protein expression of pS6K T389, pS6 S240-244. DQ661 shows anticancer activity .

HY-142656

PIM-IN-1	Pim	Cancer
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC₅₀ = 61 nM; pS6, EC₅₀ = 71 nM).

HY-107593

PS-1145 dihydrochloride	IKK	Inflammation/Immunology
PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC₅₀ value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats .

HY-124060

PS423	PDK-1	Cancer
PS423 is a prodrug of PS210, acting as a substrate-selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K. PS210 is a potent and selective PDK1 activator targeting the PIF binding pocket of PDK1 .

HY-124308

PS315	PKC	Cancer
PS315, a derivative of PS48 (HY-15967), is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing a displacement of the active site residue Lys111. PS315 inhibits the full-length and catalytic domain constructs of PKC_ζ (IC₅₀=10 μM) and PKC_η (IC₅₀=30 μM). PS315 has anti-cancer activity .

HY-157620

18:0 Lyso PS sodium	Endogenous Metabolite	Metabolic Disease
18:0 Lyso PS sodium is a bioactive molecule with the activity of promoting cell signaling. 18:0 Lyso PS sodium plays an important role in regulating the fluidity and integrity of cell membranes. 18:0 Lyso PS sodium is widely used in lipidomics research to analyze lipid metabolism in cells.

HY-15931

TMB-PS TMBZ-PS	Fluorescent Dye	Others
TMB-PS(102062-36-2) is N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt; White - pale yellow crystalline powder, soluble in water, can be used under neutral, acidic and alkaline conditions.

HY-148978A

18:0,18:1 PS	Exosomes Liposome Endogenous Metabolite	Metabolic Disease
18:0,18:1 PS is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-50882A

ELN318463 racemate	γ-secretase	Neurological Disease
ELN318463 racemate is the racemate of ELN318463. ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC₅₀s of 12nM and 656 nM for PS1and PS2, respectively. ELN318463 is 51-fold more selective for PS1 .

HY-108338

PF-05139962	mTOR	Cancer
PF-05139962 is a cyclic sulfone mTOR kinase inhibitor. PF-05139962 exhibits potent mTOR (K_i = 5 nM, pS473 IC₅₀ = 48 nM, pS6 IC₅₀ = 6 nM) inhibitory activity and high selectivity .

HY-N5002

(+)-Viroallosecurinine	Bacterial	Infection
(+)-Viroallosecurinine, a cytotoxic alkaloid, exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus . Antibacterial activity .

HY-W013758

TMB-PS sodium TMBZ-PS sodium	Biochemical Assay Reagents	Cancer
TMB-PS (TMBZ-PS) sodium is a chromogenic substrate for the detection and quantification of peroxidase activity .

HY-18008R

PS-1145 (Standard)	IKK Apoptosis	Cancer
PS-1145 (Standard) is the analytical standard of PS-1145. This product is intended for research and analytical applications. PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-148978

18:0,18:1 PS sodium	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Exosomes Endogenous Metabolite Liposome
18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-N0409

Picroside III 1 Publications Verification	Monophenols Iridoids Classification of Application Fields Terpenoids Phenols Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields Source Classification	Others
Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-N3001

Isolinderalactone 1 Publications Verification	Classification of Application Fields Terpenoids Sesquiterpenes Plants Lauraceae Lindera aggregata (Sims) Kosterm. Disease Research Fields Source Classification Cancer	STAT VEGFR Bcl-2 Family Survivin IAP NF-κB Apoptosis Caspase
Isolinderalactone is a sesquiterpene that exhibits anti-cancer, anti-inflammatory, and neuroprotective effects. Isolinderalactone inhibits VEGF expression and tyrosine phosphorylation of VEGFR2. Isolinderalactone decreases viability and induces apoptosis in U-87 glioblastoma (GBM) cells and colorectal cancer (CRC) cells. Isolinderalactone induces G2/M phase cell cycle arrest, ROS generation, pJNK/p38 MAPK activation, in colorectal cancer (CRC) cells. Isolinderalactone blocks LPS (HY-D1056)-induced NF-κB activation while activating Nrf2-HMOX1 signaling in RAW264.7 macrophages. Isolinderalactone improves cognitive dysfunction in APP/PS1 mice. Isolinderalactone can be used for the study of Glioblastoma multiforme (GBM), colorectal cancer, Alzheimer’s disease and acute lung injury .

HY-N1414A

3′,6-Disinapoylsucrose 2 Publications Verification	Natural Products Polymer products Plants Brassicaceae Raphanus sativus Linn.	Bcl-2 Family Apoptosis
3′,6-Disinapoylsucrose is a type of oligosaccharide that's effective when taken orally, and it has antidepressant, anti-anxiety, and antioxidant properties. 3′,6-Disinapoylsucrose inhibits neuronal apoptosis by lowering the ratio of Bax to Bcl-2 in hippocampal neurons, and it enhances cognitive function in APP/PS1 transgenic mice by activating the CREB/BDNF signaling pathway .

HY-148977

18:0,22:6 PS sodium	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Endogenous Metabolite
18:0,22:6 PS sodium is a lipid component of synaptic vesicles and cholesterol, which can be used for metabolic research .

HY-N5002

(+)-Viroallosecurinine	Infection Alkaloids Classification of Application Fields Pyridine Alkaloids Euphorbiaceae Plants Disease Research Fields Flueggea virosa (Roxb. ex Willd.) Voigt Source Classification	Bacterial
(+)-Viroallosecurinine, a cytotoxic alkaloid, exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus . Antibacterial activity .

HY-N15991

4ME 16:0 PS sodium	Lipid	Biochemical Assay Reagents
4ME 16:0 PS sodium is a diphytanoyl lipid.

HY-148978R

18:0,18:1 PS sodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Exosomes Endogenous Metabolite Liposome
Resorantel (Standard) is the analytical standard of Resorantel. This product is intended for research and analytical applications. 18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-N0409R

Picroside III (Standard)	Structural Classification Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Source Classification	Reference Standards Others
Picroside III (Standard) is the analytical standard of Picroside III. This product is intended for research and analytical applications. Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-N15999

18:1-12:0 Biotin PS ammonium	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PS ammonium is a biotinylated lipid.

HY-W725301

18:1(n9)-16:0 PS - IsoPure sodium	Lipid	Biochemical Assay Reagents
18:1(n9)-16:0 PS-IsoPure sodium is an isomerically pure mixed-acyl glycerophospholipid.

Cat. No.	Product Name	Chemical Structure

HY-W011338S

Benzyl butyl phthalate-d4

Benzyl butyl phthalate-d₄ is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .

HY-10227S

Bortezomib-d8

Bortezomib-d₈ is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .

HY-146885S

16:0-18:1 PS-d31 sodium 1 Publications Verification
16:0-18:1 PS-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PS (sodium).

HY-143675S

1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d9
1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d₉ is the deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS .

HY-167592S

17:0-20:3 PS-d5
17:0-20:3 PS-d₅ (1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d₅)-3-phospho- L-serine (sodium)) is deuterium labeled 17:0-20:3 PS .

HY-W042357S

Ac-rC Phosphoramidite-15N
Ac-rC Phosphoramidite- ¹⁵N is ¹⁵N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S2

Ac-rC Phosphoramidite-15N3
Ac-rC Phosphoramidite- ¹⁵N₃ is ¹⁵N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S1

Ac-rC Phosphoramidite-15N2
Ac-rC Phosphoramidite- ¹⁵N₂ is ¹⁵N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S4

Ac-rC Phosphoramidite-13C9
Ac-rC Phosphoramidite- ¹³C₉ is ¹³C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S5

Ac-rC Phosphoramidite-13C,d1
Ac-rC Phosphoramidite- ¹³C,d₁ is deuterium and ¹³C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S6

Ac-rC Phosphoramidite-13C9,15N3
Ac-rC Phosphoramidite- ¹³C₉, ¹⁵N₃ is ¹³C and ¹⁵N-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-W042357S3

Ac-rC Phosphoramidite-13C2,d1
Ac-rC Phosphoramidite- ¹³C₂,d₁ is deuterium and ¹³C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

HY-145539S

1,2-Dipalmitoyl-sn-glycero-3-PS-d62 sodium salt
1,2-Dipalmitoyl-sn-glycero-3-PS-d₆₂ sodium is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-PS sodium (HY-145539). 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is used for the preparation of phospholipid bilayers .

HY-145539SA

1,2-Dipalmitoyl-sn-glycero-3-PS-d62 ammonium
1,2-Dipalmitoyl-sn-glycero-3-PS-d₆₂ ammonium is the deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-PS ammonium. 1,2-Dipalmitoyl-sn-glycero-3-PS is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS is used for the preparation of phospholipid bilayers.

HY-178754S

12-Dipalmitoyl-sn-glycero-3-PS-d3 ammonium
12-Dipalmitoyl-sn-glycero-3-PS-d₃ ammonium is the deuterium labeled 12-Dipalmitoyl-sn-glycero-3-PS ammonium.

HY-173090S

VAVVR(pT)PPK(pS)PSSAK-(Lys-13C6,15N2) TFA
VAVVR(pT)PPK(pS)PSSAK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled VAVVR(pT)PPK(pS)PSSAK-(Lys) TFA.

HY-178737S

1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d₃ ammonium (18:2 PS-d₃ ammonium) is the deuterium labeled 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine ammonium.

Cat. No.	Product Name	Target	Research Areas	Chemical Structure