11 Results for "

Parishin

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Parishin" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N2031
CAS No.: 62499-28-9
Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway .
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1 Cited Publications
Cat. No.: HY-N2124
CAS No.: 174972-79-3
Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities . Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3 . Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells [1][2][3]. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis [3].
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Cat. No.: HY-N2125
CAS No.: 174972-80-6
Parishin C is a brain-penetrant major bioactive component found in Gastrodia elata Blume. Parishin C is a 5-HT1A receptor agonist with an EC50 of 34 nM. Parishin C has antipsychotic and neuroprotective effects. Parishin C protects against Aβ-induced long-term potentiation damage and NMDA receptor current impairment. Parishin C reduces oxidative stress, pro-inflammatory cytokine levels, caspase activity, brain water content, and cerebral infarct volume; increases antioxidant enzyme activity and BDNF levels; improves nerve function and histopathological brain damage. Parishin C attenuates phencyclidine-induced immobility time increases, sociability deficits, and visual recognition memory impairment. Parishin C can be used for the research of ischemic stroke, Alzheimer's disease, and schizophrenia-like psychosis .
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Cat. No.: HY-N2126
CAS No.: 952068-57-4
Parishin E is a modulator of hexokinase 2, lactate dehydrogenase A, and silent information regulator 6 (sirtuin 6), and is also a component present in Gastrodia elata Blume . Parishin E reduces the expression of hexokinase 2 and lactate dehydrogenase A, thereby regulating the process of cellular glycolysis . Parishin E regulates the deacetylation mediated by silent information regulator 6 (Sirtuin 6), and inhibits histone 3 lactylation modifications at the H3K18la and H3K27la sites . Parishin E inhibits macrophage polarization . Parishin E alleviates LPS-induced inflammatory responses and suppresses the expression of pro-inflammatory cytokines . Parishin E exerts ameliorating effects on rheumatoid arthritis . Parishin E can be used in studies related to rheumatoid arthritis .
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Cat. No.: HY-N12395
CAS No.: 952283-93-1
Parishin G is a Parishin (HY-N2031) derivative that can be isolated from Gastrodia elata. Parishin G has antioxidant activity .
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Cat. No.: HY-N2124R
CAS No.: 174972-79-3
Parishin B (Standard) is the analytical standard of Parishin B. This product is intended for research and analytical applications. Parishin B is a parishin metabolite that can be isolated from Gastrodia elata with antioxidant activity .
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Cat. No.: HY-N2126R
CAS No.: 952068-57-4
Parishin E (Standard) is the analytical standard of Parishin E. This product is intended for research and analytical applications. Parishin E, a parishin derivative isolated from Gastrodia elata, may have antioxidant property .
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Cat. No.: HY-N2031R
CAS No.: 62499-28-9
Parishin (Standard) is the analytical standard of Parishin. This product is intended for research and analytical applications. Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway .
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Cat. No.: HY-N12019
CAS No.: 1971915-61-3
Parishin K is a cardioprotective agent obtained from the roots of Gastrodia elata Bl. Parishin K can be used in cardiovascular disease research .
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Cat. No.: HY-N2125R
CAS No.: 174972-80-6
Parishin C (Standard) is the analytical standard of Parishin C (HY-N2125). This product is intended for research and analytical applications. Parishin C is a brain-penetrant major bioactive component found in Gastrodia elata Blume. Parishin C is a 5-HT1A receptor agonist with an EC50 of 34 nM. Parishin C has antipsychotic and neuroprotective effects. Parishin C protects against Aβ-induced long-term potentiation damage and NMDA receptor current impairment. Parishin C reduces oxidative stress, pro-inflammatory cytokine levels, caspase activity, brain water content, and cerebral infarct volume; increases antioxidant enzyme activity and BDNF levels; improves nerve function and histopathological brain damage. Parishin C attenuates phencyclidine-induced immobility time increases, sociability deficits, and visual recognition memory impairment. Parishin C can be used for the research of ischemic stroke, Alzheimer's disease, and schizophrenia-like psychosis .
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