4 Results for "

Parishin C

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Parishin C" in MCE Product Catalog:

1
Parishin B
Parishin B
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1 Cited Publications
Cat. No.: HY-N2124
CAS No.: 174972-79-3
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Ferroptosis Apoptosis

Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities . Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3 . Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells [1][2][3]. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis [3].
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Parishin C
Parishin C
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Cat. No.: HY-N2125
CAS No.: 174972-80-6
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants

Target:  

5-HT Receptor iGluR Caspase Interleukin Related TNF Receptor SOD NF-κB

Parishin C is a brain-penetrant major bioactive component found in Gastrodia elata Blume. Parishin C is a 5-HT1A receptor agonist with an EC50 of 34 nM. Parishin C has antipsychotic and neuroprotective effects. Parishin C protects against Aβ-induced long-term potentiation damage and NMDA receptor current impairment. Parishin C reduces oxidative stress, pro-inflammatory cytokine levels, caspase activity, brain water content, and cerebral infarct volume; increases antioxidant enzyme activity and BDNF levels; improves nerve function and histopathological brain damage. Parishin C attenuates phencyclidine-induced immobility time increases, sociability deficits, and visual recognition memory impairment. Parishin C can be used for the research of ischemic stroke, Alzheimer's disease, and schizophrenia-like psychosis .
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Parishin C (Standard)
Parishin C (Standard)
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Cat. No.: HY-N2125R
CAS No.: 174972-80-6
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants

Target:  

Reference Standards 5-HT Receptor iGluR Caspase Interleukin Related TNF Receptor SOD NF-κB

Parishin C (Standard) is the analytical standard of Parishin C (HY-N2125). This product is intended for research and analytical applications. Parishin C is a brain-penetrant major bioactive component found in Gastrodia elata Blume. Parishin C is a 5-HT1A receptor agonist with an EC50 of 34 nM. Parishin C has antipsychotic and neuroprotective effects. Parishin C protects against Aβ-induced long-term potentiation damage and NMDA receptor current impairment. Parishin C reduces oxidative stress, pro-inflammatory cytokine levels, caspase activity, brain water content, and cerebral infarct volume; increases antioxidant enzyme activity and BDNF levels; improves nerve function and histopathological brain damage. Parishin C attenuates phencyclidine-induced immobility time increases, sociability deficits, and visual recognition memory impairment. Parishin C can be used for the research of ischemic stroke, Alzheimer's disease, and schizophrenia-like psychosis .
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Parishin C (terpene)
Parishin C (terpene)
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Cat. No.: HY-N20644
CAS No.: 74636-03-6
Category:  

Terpenoids Sesquiterpenes Asteraceae Plants Artemisia ludoviciana Nutt.

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