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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PiT-2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PiT-2" in MCE Product Catalog:
Cat. No.: HY-P702038
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC20A2; Sodium-dependent phosphate transporter 2; Gibbon ape leukemia virus receptor 2; GLVR-2; Phosphate transporter 2; PiT-2; PiT2; hPiT2; Solute carrier family 20 member 2
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Cat. No.: HY-159978
CAS No.: 1628848-73-6
Target:
Research Areas:
EOS789 is an orally active sodium-dependent phosphate transporter inhibitor, with IC50 values of 6.8, 1.5, and 1.7 μM against human NaPi-IIb, PiT-1, PiT-2, respectively; and IC50 values of 3.9, 1.9, and 1.7 μM against rat NaPi-IIb, PiT-1, PiT-2, respectively. EOS789 inhibits intestinal phosphate absorption, increases fecal phosphate excretion, reduces urinary phosphate excretion, and decreases the levels of serum phosphate, FGF23, and adult parathyroid hormone. EOS789 ameliorates ectopic thoracic aortic calcification, renal injury and hyperphosphatemia, and inhibits the expression of fibrosis markers. EOS789 can be used for the research of hyperphosphatemia and chronic kidney disease-mineral and bone disorder (CKD-MBD) [2].
Cat. No.: HY-RS13060
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Research Areas:
SLC20A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC20A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
