2 Results for "

Ponalrestat

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ponalrestat" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-106697
CAS No.: 72702-95-5
Purity:  99.51%
Synonyms: ICI 128436
Target:  

Aldose Reductase

Research Areas:  

Metabolic Disease

Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol .
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Cat. No.: HY-106697R
CAS No.: 72702-95-5
Synonyms: ICI 128436 (Standard)
Research Areas:  

Metabolic Disease

Ponalrestat (Standard) (ICI 128436 (Standard)) is the analytical standard of Ponalrestat (HY-106697). This product is intended for research and analytical applications. Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol .
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