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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
RIN1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "RIN1" in MCE Product Catalog:
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RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation [1].
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1 Cited Publications
CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.
Cat. No.: HY-RS11982
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RIN1 Human Pre-designed siRNA Set A contains three designed siRNAs for RIN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17055
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Rin1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rin1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23499
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Rin1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rin1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-149014
CAS No.: 2639148-08-4
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OX2R-IN-1 (compound 15) is a low cytotoxicity profile OX2R-IN-1 antagonist (a potential OX2R binder) with an IC50 value of 484 μM. OX2R-IN-1 (compound 15) can cross the BBB into the brain with a short half-life [1].
Cat. No.: HY-149358
CAS No.: 2854331-14-7
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NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model [1].
Cat. No.: HY-176405
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σ1R-IN-1 ((R,R)-1a) is a potent σ-1R inhibitor with an IC50 of 110 nM. σ1R-IN-1 is promising for research of neuropsychiatric disorders [1].
Cat. No.: HY-100328
CAS No.: 1257555-79-5
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CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.
Cat. No.: HY-159941
CAS No.: 2200453-71-8
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tau-0N4R-IN-1 (Compound 6T) is an BBB-penetrable inhibitor of tau 0N4R oligomerization. tau-0N4R-IN-1 effectively inhibits the fibrosis of tau 0N4R, 2N3R, and 2N4R, exhibits an anti-seeding effect on tau in vitro, reduces the oligomerization of α-syn dose-dependently, and prevents formation of α-syn inclusions. tau-0N4R-IN-1 is stable in mouse microsomes and reduces Aβ plaques in brain tissues from AD patients. tau-0N4R-IN-1 has good pharmacokinetic properties in mice [1].
Cat. No.: HY-170687
CAS No.: 2896132-06-0
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AT2R-IN-1 (A-174) is a AT2R inhibitor, used in the research of neuropathic pain [1].
Cat. No.: HY-101774R
CAS No.: 2095849-04-8
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CSF1R-IN-1 (Standard) is the analytical standard of CSF1R-IN-1 (HY-101774). This product is intended for research and analytical applications. CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
