2 Results for "

RWJ58643

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RWJ58643" in MCE Product Catalog:

Cat. No.: HY-19472
CAS No.: 287183-00-0
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

RWJ-58643 is a β-trypsin inhibitor that suppresses allergic inflammation. RWJ-58643 (100 mg) significantly reduced nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 resulted in late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 modulates allergic responses by inhibiting the release of β-trypsin from mast cells .
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Cat. No.: HY-19472A
CAS No.: 287182-52-9
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

RWJ-58643 hydrochloride is a β-trypsin inhibitor that inhibits allergic inflammation. RWJ-58643 hydrochloride (100 mg) significantly reduces nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 hydrochloride causes late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 hydrochloride modulates allergic reactions by inhibiting the release of β-trypsin from mast cells.
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