RWJ-58643 hydrochloride
RWJ-58643 hydrochloride is a β-trypsin inhibitor that inhibits allergic inflammation. RWJ-58643 hydrochloride (100 mg) significantly reduces nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 hydrochloride causes late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 hydrochloride modulates allergic reactions by inhibiting the release of β-trypsin from mast cells.
For research use only. We do not sell to patients.
- CAS No.: 287182-52-9
- Formula: C20H27ClN6O4S
- Molecular Weight:482.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 287182-52-9
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Molecular Weight 482.98
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Formula C20H27ClN6O4S
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SMILES
O=C([C@H]1N(C[C@@H](C1)O)C(C)=O)NC(CCCNC(N)=N)C(C2=NC3=CC=CC=C3S2)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RWJ-58643 hydrochloride Related Classifications
HY-19472A Related Classifications
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