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Results for "

SMPD2

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Natural
Products

1

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS13448
    SMPD2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SMPD2 Human Pre-designed siRNA Set A contains three designed siRNAs for SMPD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SMPD2 Human Pre-designed siRNA Set A
    SMPD2 Human Pre-designed siRNA Set A
  • HY-134505
    Avicin G

    		Ras NF-κB Cancer
    Avicin G is a sphingomyelinase inhibitor and plasma membrane disruptor. Avicin G inhibits the enzymatic activities of neutral sphingomyelinases (SMPD2/3) and acid sphingomyelinase (SMPD1), elevates intracellular sphingomyelin levels, and alters the distribution of sphingomyelin. Avicin G interferes with the lateral segregation of GTP- and GDP-bound H-Ras, inhibits the signal output of oncogenic K-Ras and H-Ras, reduces the phosphorylation of ERK and Akt, increases lysosomal pH, and inhibits the endocytic recycling of epidermal growth factor receptor. Avicin G can be used in research related to pancreatic ductal adenocarcinoma and non-small cell lung cancer .
    Avicin G

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