4 Results for "

SMPD2

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SMPD2" in MCE Product Catalog:

Cat. No.: HY-RS13448
Research Areas:  

Others

SMPD2 Human Pre-designed siRNA Set A contains three designed siRNAs for SMPD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P811320
Synonyms: Sphingomyelin phosphodiesterase 2, Lyso-platelet-activating factor-phospholipase C, Neutral sphingomyelinase, Lyso-PAF-PLC, N-SMase, nSMase, nSMase1, SMPD2

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-134505
CAS No.: 197787-17-0
Avicin G is a sphingomyelinase inhibitor and plasma membrane disruptor. Avicin G inhibits the enzymatic activities of neutral sphingomyelinases (SMPD2/3) and acid sphingomyelinase (SMPD1), elevates intracellular sphingomyelin levels, and alters the distribution of sphingomyelin. Avicin G interferes with the lateral segregation of GTP- and GDP-bound H-Ras, inhibits the signal output of oncogenic K-Ras and H-Ras, reduces the phosphorylation of ERK and Akt, increases lysosomal pH, and inhibits the endocytic recycling of epidermal growth factor receptor. Avicin G can be used in research related to pancreatic ductal adenocarcinoma and non-small cell lung cancer .
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Cat. No.: HY-P702447
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Sphingomyelin phosphodiesterase 2; Lyso-platelet-activating factor-phospholipase C; Lyso-PAF-PLC; Neutral sphingomyelinase; N-SMase; nSMase; nSMase1
Species:  
Source:  
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