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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
SP2
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "SP2" in MCE Product Catalog:
Cat. No.: HY-W353469
CAS No.: 22160-26-5
Synonyms: Glucosylglycerol
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Cat. No.: HY-P10604
CAS No.: 678138-45-9
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Cat. No.: HY-RS13605
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SP2 Human Pre-designed siRNA Set A contains three designed siRNAs for SP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17158
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Sp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23608
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Sp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5870
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Cat. No.: HY-N10208
CAS No.: 1216840-17-3
Category:
Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism Cancer
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Cat. No.: HY-N17267
CAS No.: 17942-08-4
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Cat. No.: HY-155176
CAS No.: 2364448-93-9
SP-2-225 is a selective HDAC6 inhibitor. SP-2-225 enhance the production of cancer-associated antigens and macrophage antigen cross-presentation to T cells. SP-2-225 reduces the tumor volume in a syngeneic SM1 melanoma model .
Cat. No.: HY-173132
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AKR1Cs-IN-1 (Compound 29) is a potent and broad-spectrum inhibitor targeting members of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). By simultaneously occupying the SP2 and SP3 pockets, it effectively inhibits multiple isoforms and disrupts metabolic pathways associated with drug resistance. In enzymatic activity assays, AKR1Cs-IN-1 exhibited significant inhibitory potency, with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM against AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. In the doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, AKR1Cs-IN-1 showed remarkable resensitization effects and significantly enhanced the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on overcoming drug resistance in breast cancer .
Cat. No.: HY-176005
Synonyms: SP-dADP-α-S sodium
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Sp-2'-Deoxyadenosine-5'-O-(1-thiodiphosphate) (Sp-dADP-α-S) sodium is an isomer of Rp-2'-Deoxyadenosine-5'-O-(1-thiodiphosphate) sodium (HY-176004) .
Cat. No.: HY-RS13635
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SPATA1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPATA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176004
Synonyms: Rp-dADP-α-S sodium
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Rp-2'-Deoxyadenosine-5'-O-(1-thiodiphosphate) (Rp-dADP-α-S) sodium is an isomer of Sp-2'-Deoxyadenosine-5'-O-(1-thiodiphosphate) sodium (HY-176005) .
Cat. No.: HY-162258
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AChE-IN-57 (compound 5b(SP-2)) is a potent AChE inhibitor. AChE-IN-57 improves cognitive defects. AChE-IN-57 restores the biochemical mediators and inhibits reactive oxygen and nitrogen species implicated in the neuroinflammation mechanism. AChE-IN-57 has the potential for the research of Alzheimer .
Cat. No.: HY-137651A
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Sp-2'-F-dATP-αS tetrasodium is a dATP (HY-136648) derivative. Sp-2'-F-dATP-αS tetrasodium can be used in cancer research.
Cat. No.: HY-137649A
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Sp-2'-O-Me-CTPαS tetrasodium is an analog of CTP. Sp-2'-O-Me-CTPαS tetrasodium can be used enzymatically to introduce thiophosphate and modified 2'-OH groups into RNA.
Cat. No.: HY-137648A
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Sp-2'-O-Me-GTPαS tetrasodium is an analog of GTP (HY-113225). Sp-2'-O-Me-GTPαS tetrasodium can be used for the enzymatic incorporation of thiophosphate and modified 2'-OH groups into RNA.
Cat. No.: HY-P11599
Cat. No.: HY-181853
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NOTA-SP₂A-PSMAL is a ligand targeting prostate-specific membrane antigen (PSMA), which competitively binds to PSMA with high binding affinity and an IC50 value of 0.26 nM. 18F-labeled NOTA-SP2A-PSMAL can be used as a PET tracer for positron emission tomography imaging of prostate cancer. NOTA-SP2A-PSMAL can be used for the synthesis and research of radionuclide conjugates (RDCs) .
Cat. No.: HY-181066
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ACE2-SP PPI-IN-1 is an inhibitor of the interaction between the SARS-CoV-2 spike protein and ACE2, with an IC50 of 2162.77 nM. ACE2-SP PPI-IN-1 exhibits low cytotoxicity in human fibroblasts. ACE2-SP PPI-IN-1 binds to the interface region between the spike protein RBD and ACE2, reducing the flexibility of the critical receptor-binding loop and maintaining the structural compactness of the spike protein. ACE2-SP PPI-IN-1 can be used for research related to SARS-CoV-2 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
