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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
SPDP Crosslinker
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "SPDP Crosslinker" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: SPDP Crosslinker; Py-ds-Prp-OSu
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SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
Cat. No.: HY-126495
CAS No.: 150244-18-1
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Sulfo-LC-SPDP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
Cat. No.: HY-100216R
CAS No.: 68181-17-9
Synonyms: SPDP Crosslinker (Standard); Py-ds-Prp-OSu (Standard)
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SPDP (Standard) is the analytical standard of SPDP (HY-100216). This product is intended for research and analytical applications. SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
Cat. No.: HY-W800714
CAS No.: 2655474-48-7
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SPDP-Gly-Gly-methoxy is a linker with SPDP and methyl ester moiety. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions.
Cat. No.: HY-W800711
CAS No.: 2655501-79-2
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SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.
Cat. No.: HY-W800713
CAS No.: 2655501-78-1
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SPDP-Gly-Pro-acid is a linker with SPDP and carboxylic acid moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
