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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Specific active probe
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Specific active probe" in MCE Product Catalog:
3
Research Areas:
Cat. No.: HY-176268
Synonyms: RA-0188293; RA-NSP2-1
Research Areas:
SGC-NSP2hel-1 (RA-0188293), a chemical probe, is a potent, specific and orally active nsP2 inhibitor. SGC-NSP2hel-1 has broad spectrum activity against multiple alphaviruses of the nsP2 helicase with a CC50 > 250 μM.
SGC-NSP2hel-1 (RA-0188293) shows selectivity index > 4000 against human
RNA helicases. SGC-NSP2hel-1 reduces virus replication and limited virus-induced pathology by forming a stable complex with nsP2 and ATP in a preclinical small animal model of CHIKV disease.
Cat. No.: HY-P11331
CAS No.: 1356828-49-3
Target:
Research Areas:
Cat. No.: HY-135280
CAS No.: 852315-00-5
Synonyms: CB1 inverse agonist 1
Target:
Research Areas:
MRL-650 (CB1 inverse agonist 1), a chemical probe, is a highly potent, orally active, and specific inverse agonist of CB1 receptor with IC50s of 7.5 nM and 4100 nM for CB1 and CB2 receptors, respectively. Anorexigenic effects .
Cat. No.: HY-W123012
CAS No.: 1643841-88-6
Synonyms: 3-(4-Azidophenyl)propiolonitrile
Target:
APN-Azide (3-(4-Azidophenyl)propiolonitrile) is a codon-active compound that can achieve specific labeling of target molecules in biological systems through its unique chemical structure. APN-Azide can be used for bioimaging and the development of molecular probes to study biological processes within cells.
Cat. No.: HY-124610
CAS No.: 2244425-14-5
Target:
Research Areas:
DKFZ-633 is a potent KLK6 inhibitor and KLK6-specific probe with an IC50 of 250 nM against human KLK6. DKFZ-633 covalently labels active KLK6 in a specific manner, and successfully pulls down and captures endogenous active KLK6 from cell-conditioned media. DKFZ-633 serves as a critical tool for investigating the function of KLK6 and its regulatory mechanisms in head and neck cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
