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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
Streptomyces metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "Streptomyces metabolite" in MCE Product Catalog:
Synonyms: Omuralide; β-Clastolactacystin
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Cat. No.: HY-W102907
CAS No.: 4551-72-8
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Pyrrole-2-carboxamide (Compound 26) is a secondary metabolite. Pyrrole-2-carboxamide can be produced by two mangrove-derived actinomycetes Streptomyces sp. WHUA03072 and Streptomyces sp. WHUA03267 .
Cat. No.: HY-N6795
CAS No.: 87081-36-5
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Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Cat. No.: HY-134090
CAS No.: 51867-94-8
Synonyms: Antibiotic TS 885; NSC 248958
9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
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Infection Natural Products Microorganisms Monophenols Marine natural products Phenols Disease Research Fields Marine microorganism
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Cat. No.: HY-N15080
CAS No.: 57528-68-4
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Cat. No.: HY-W067479
CAS No.: 22031-64-7
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Simaroubaceae Simple Phenylpropanols Other Diseases Phenylpropanoids Plants Disease Research Fields Picrasma quassioides(D．Don)Benn．
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Cat. No.: HY-W060074
CAS No.: 50892-83-6
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Infection Alkaloids Microorganisms Pyridine Alkaloids Disease Research Fields Indole Alkaloids
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Cat. No.: HY-134666A
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Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites .
Sparsomycin is a metabolite of the bacterium Streptomyces sparsogenes. Sparsomycin inhibits protein synthesis in both eukaryotic cells and bacteria. Sparsomycin inhibits the translation extension of ribosome PTC .
Cat. No.: HY-W747516
CAS No.: 352304-41-7
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Cat. No.: HY-W002038
CAS No.: 56613-80-0
Synonyms: D-Phenylglycinol; (-)-Phenylglycinol
(R)-(-)-2-Phenylglycinol (D-Phenylglycinol; (-)-Phenylglycinol) is a chiral β-amino alcohol, a starting material for chiral synthesis, and a potential nematicide. (R)-(-)-2-Phenylglycinol exhibits nematicidal and egg hatching inhibitory activity against the southern root-knot nematode (Meloidogyne incognita), and is also an upregulated metabolite in the fermentation broth of Streptomyces aquilus JXGZ01. (R)-(-)-2-Phenylglycinol can be used as a framework for constructing zwitterionic bicyclic lactams and multi-substituted piperidine/piperidine acid drugs. (R)-(-)-2-Phenylglycinol can be used in drug synthesis and nematode infection-related research .
Cat. No.: HY-N8504
CAS No.: 59795-94-7
Synonyms: NSC 260179; Spectinabilin
Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50=13 μM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50=1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s=34.3, 47, and 37.2 μg/mL, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50=0.84 μg/mL) and increases survival of P. densiflora trees inoculated with B. xylophilus.
Cat. No.: HY-N12900
CAS No.: 55062-34-5
Synonyms: Tryptophandehydrobutyrine diketopiperazine
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Cat. No.: HY-W491891
CAS No.: 13398-79-3
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Cat. No.: HY-155953
CAS No.: 959150-61-9
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6-epi-COTC is a diastereoisomer of Streptomyces metabolite with a anti-cancer activitie .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
