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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Syngap1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Syngap1" in MCE Product Catalog:
Cat. No.: HY-RS14089
Target:
Research Areas:
SYNGAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SYNGAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20656
Target:
Research Areas:
Syngap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Syngap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27167
Target:
Research Areas:
Syngap1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Syngap1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71619
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Syngap1; Synaptic Ras GTPase Activating Protein 1 Homolog (Rat); Synaptic Ras GTPase Activating Protein 1; Synaptic Ras GTPase Activating Protein 1 Homolog; KIAA1938; Synaptic Ras GTPase Activating Protein, 135kDa; Syngap; Synaptic Ras GTPase-Activating P
Species:
Human
Source:
E. coli
Cat. No.: HY-P81944A
Synonyms: KIAA1938; Syngap1; Ras/Rap GTPase-activating protein Syngap; Neuronal RasGAP; Synaptic Ras GTPase-activating protein 1; Synaptic Ras-GAP 1
Cat. No.: HY-180779
CAS No.: 2636710-78-4
Research Areas:
SR-1815 is a multi-kinase inhibitor of CLK1 (IC50 446 nM), CLK2 (605 nM), and CLK3 (6.8 μM; weaker). SR-1815 reduces SR protein phosphorylation and Syngap1 toxic exon inclusion, restores SynGAP and postsynaptic PSD95/GluN1 expression, and promotes dendritic spine enlargement and branching. SR-1815 decreases synaptic/circuit hyperexcitability. SR-1815 selectively inhibits cancer cell line proliferation. SR-1815 can be used for research on epileptic encephalopathy [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
