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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Synthetic methods
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Synthetic methods" in MCE Product Catalog:
Cat. No.: HY-W017708
CAS No.: 217-59-4
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Triphenylene is a highly symmetrical polycyclic aromatic hydrocarbon. Triphenylene shows no carcinogenic activity in mouse skin application experiments. Triphenylene can be used as a drug intermediate for the synthesis of triphenyl polycyclic aromatic hydrocarbons (PAHs) .
Cat. No.: HY-117910
CAS No.: 125279-72-3
(-)-Lentiginosine is a compound that can be obtained by a specific synthetic method.
Cat. No.: HY-B1844
CAS No.: 70124-77-5
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Flucythrinate is a synthetic pyrethroid with endocrine suppressive properties. Flucythrinate showed good binding affinity to the vitamin D nuclear receptor (VDR) with a score of -11.0 kcal/mol. Flucythrinate has been proposed as a multi-target ligand that may interact with several proteins associated with breast cancer. The screening method for Flucythrinate showed good accuracy in binding site prediction and affinity estimation .
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Homocholic acid is a synthetic steroid analogue. Homocholic acid can be labeled with 75Se and is used for SeHCAT detection (a method for diagnosing bile acid malabsorption) .
Cat. No.: HY-L0115V
10,091 compounds
ASINEX has elaborated a library of diverse macrocycles using an effective tool box of synthetic methods. The resulting scaffolds are novel, tremendously diverse, medchem-relevant, macrocyclic frameworks.
Macrocyles tend to be larger than traditional screening molecules which make them perfect discovery tools for targets with shallow or extended binding sites. At the same time, their unique character based on restricted flexibility and ability to form intra-molecular hydrogen bonds allows for design approaches effectively optimizing properties such asaqueous solubility and membrane permeability. Many of these macrocycles have been tested for aqueous and DMSO solubility with cut-offs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4) followed by PAMPA permeability assay.
Cat. No.: HY-W008484
CAS No.: 150114-71-9
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Aminopyralid is a synthetic auxin herbicide. Aminopyralid provides foliar and soil residual weed control, and also increases forage yield in bahiagrass pastures. When present as a soil residue, Aminopyralid causes phytotoxicity, reduced plant height, decreased flower number and fruit yield loss in rotated vegetable crops. Aminopyralid is registered for the control of annual and perennial broadleaf weeds in pastures, permanent grasslands and non-cropped areas .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
