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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
T-currents
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "T-currents" in MCE Product Catalog:
1
Cat. No.: HY-W032013S1
CAS No.: 78510-02-8
Synonyms: Octanol-d2
Cat. No.: HY-W032013R
CAS No.: 111-87-5
Synonyms: Octanol (Standard)
Cat. No.: HY-W032013S
CAS No.: 153336-13-1
Synonyms: Octanol-d17
Cat. No.: HY-W032013S2
CAS No.: 1335435-64-7
Synonyms: Octanol-d2-1
Cat. No.: HY-W032013S3
CAS No.: 3028869-76-0
Synonyms: Octanol-d5
Cat. No.: HY-W654314
CAS No.: 2519846-58-1
Synonyms: N-Acetyl-S-(phenyl-d5)-L-cysteine
Cat. No.: HY-118030
CAS No.: 1257116-00-9
Target:
Research Areas:
RQ-00311651 is a T-type calcium channel blocker that specifically targets the Cav3.2 isoform with a role in neuropathic and visceral pain. RQ-00311651 significantly inhibits T currents in HEK293 cells expressing human Cav3.1 or Cav3.2. RQ-00311651 also inhibited high potassium-induced calcium signaling. RQ-00311651 also inhibits antiallergic properties in rats and mice with neuropathic pain induced by spinal nerve injury or Paclitaxel (HY-B0015). Oral and intraperitoneal injection (10-20 mg/kg) inhibits Cerulein (HY-A0190)-induced acute pancreatitis and cyclophosphamide-induced cystitis in mice .
Cat. No.: HY-W699942
CAS No.: 1189945-12-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
