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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
TET3
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "TET3" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-402410
CAS No.: 1451750-73-4
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TETi76 is an orally active TET family inhibitor with IC50 values ??of 1.5, 9.4 and 8.8 μM for TET1, TET2 and TET3, respectively. TETi76 competitively binds to the active site of TET enzymes, reduces cytosine hydroxymethylation and restricts clonal growth of TET2 mutants in vitro and in vivo, but does not affect the growth of normal hematopoietic precursor cells. TETi76 can be used for leukemia research .
1
1 Cited Publications
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UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity .
Cat. No.: HY-W018324
CAS No.: 1123-95-1
Synonyms: 5hmC
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Cat. No.: HY-RS24852
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Tet3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tet3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14386
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TET3 Human Pre-designed siRNA Set A contains three designed siRNAs for TET3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18373
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Tet3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tet3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W018324S
Synonyms: 5hmC-13C,d2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
