11 Results for "

TSC2

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "TSC2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-134904
CAS No.: 2382769-46-0
Purity:  95.54%
Synonyms: RM-006
Target:  

mTOR

Research Areas:  

Cancer

RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors .
loading...
    loading...
Cat. No.: HY-150229
CAS No.: 2803699-70-7
Purity:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies [2].
loading...
    loading...
Cat. No.: HY-RS23540
Research Areas:  

Others

Tsc2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tsc2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-134922
CAS No.: 181373-35-3
Synonyms: REDD1 inducer-1
Target:  

Influenza Virus mTOR

Research Areas:  

Infection

NS1-IN-1 (REDD1 inducer-1) is a naphthalimide compound and an NS1 inhibitor. NS1-IN-1 antagonizes influenza A virus NS1-mediated inhibition of host gene expression and induces REDD1 expression. NS1-IN-1 suppresses the mTORC1 signaling pathway via a TSC1-TSC2 dependent mechanism. NS1-IN-1 exhibits broad antiviral activity against influenza virus and vesicular stomatitis virus (VSV), with low toxicity .
loading...
    loading...
Cat. No.: HY-RS15132
Research Areas:  

Others

TSC2 Human Pre-designed siRNA Set A contains three designed siRNAs for TSC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-155475
CAS No.: 2974368-96-0
Target:  

mTOR

Research Areas:  

Cardiovascular Disease

mTORC1-IN-2 (compound H3) is a NO donor compound that alleviates vasodilation and attenuates myocardial hypoxic injury. mTORC1-IN-2 upregulates TSC2-P expression and inhibits mTORC1 expression .
loading...
    loading...
Cat. No.: HY-RS17096
Research Areas:  

Others

Tsc2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tsc2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P86179
Synonyms: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P83292
Synonyms: TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P810584
Synonyms: TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-P810585
Synonyms: TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
  • 1