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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
TY11345
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "TY11345" in MCE Product Catalog:
Cat. No.: HY-105015
CAS No.: 137927-14-1
Target:
Research Areas:
TY-11345 is an orally active gastric mucosal H +/K +-ATPase inhibitor, with IC50 values of 5.8 μM (Reference 1) and 3.3 μM (Reference 2) at pH 6.0, respectively. TY-11345 inhibits basal gastric acid secretion stimulated by Tetragastrin (HY-125556) and Pentagastrin (HY-A0261), and prevents gastric and duodenal injuries in rats. TY-11345 can be used in the research of peptic ulcer disease and acid-related gastrointestinal diseases .
Cat. No.: HY-19153
CAS No.: 156601-79-5
Synonyms: rel-TY-11345 free base
Target:
Research Areas:
Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H +/K +-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
