5 Results for "

Ten-eleven translocation

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Ten-eleven translocation" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-122258
CAS No.: 116409-29-1
Purity:  99.27%
Target:  

STAT TET Protein

Research Areas:  

Cancer

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 (TET1) and 5-hydroxymethylcytosine (5hmC). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5 .
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Cat. No.: HY-W018324
CAS No.: 1123-95-1
Synonyms: 5hmC
5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. 5-Hydroxymethylcytosine can be used for the study of non-small cell lung cancer (NSCLC), neurodegenerative diseases (Alzheimer’s, Parkinson’s) and hematological malignancies (acute myeloid leukemia, myelodysplastic syndromes) .
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Cat. No.: HY-W396714
CAS No.: 14047-56-4
Synonyms: Wormwood acid sodium
Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten?eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research .
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Cat. No.: HY-P702914
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TET1; Methylcytosine Dioxygenase TET1; Prev. CXXC6; CXXC Zinc Finger 6; LCX; Tet Oncogene 1; Leukemia-Associated Protein With A CXXC Domain; Ten-eleven translocation 1; BA119F7.1; Ten-eleven translocation-1; KIAA1676; CXXC Finger 6; Ten-eleven Translocati
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-W018324S
Synonyms: 5hmC-13C,d2
5-Hydroxymethylcytosine- 13C,d2 is the 13C and deuterium labeled 5-Hydroxymethylcytosine (HY-W018324). 5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. 5-Hydroxymethylcytosine can be used for the study of non-small cell lung cancer (NSCLC), neurodegenerative diseases (Alzheimer’s, Parkinson’s) and hematological malignancies (acute myeloid leukemia, myelodysplastic syndromes) .
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