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Tubulin-IN-68

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-183762
    Tubulin-IN-68

    		Microtubule/Tubulin Apoptosis Cancer
    Tubulin-IN-68 is a tubulin inhibitor with an IC50 of 19.3 μM. Tubulin-IN-68 exhibits antiproliferative activity against human cancer cells. Tubulin-IN-68 induces G2/M phase cell cycle arrest. Tubulin-IN-68 induces apoptosis. Tubulin-IN-68 can be used in the research of colorectal cancer, hepatocellular carcinoma, breast cancer, and T-cell leukemia .
    Tubulin-IN-68
  • HY-163983
    Tubulin polymerization-IN-68

    		Microtubule/Tubulin Apoptosis PARP Caspase Cancer
    Tubulin polymerization-IN-68 (compound 32) is a tubulin inhibitor that can inhibit tubulin polymerization and destroy the cellular microtubule network. Tubulin polymerization-IN-68 can upregulate the expression of PARP-1 and caspase-3 and induce cell apoptosis, and has anticancer activity. Tubulin polymerization-IN-68 can effectively inhibit HepG2 (IC50=93 nM) and significantly inhibit the growth of HepG2 xenograft tumors in nude mice by oral administration .
    Tubulin polymerization-IN-68

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