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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Ube3a
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Ube3a" in MCE Product Catalog:
Synonyms: RG6091; RO7248824
Target:
Research Areas:
Rugonersen (RG6091; RO7248824) is a locked-nucleic acid (LNA)- modified antisense oligonucleotides (ASOs), and results in reduction of ubiquitin-protein ligase E3A (UBE3A) silencing. Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, Rugonersen has been used for AS reasearch .
Cat. No.: HY-162683
CAS No.: 437982-89-3
Target:
Research Areas:
(S)-PHA533533 is a CDK2 and CDK5 inhibitor with blood-brain barrier permeability, with IC50 values of 37 nM and 55 nM, respectively. (S)-PHA533533 effectively restores UBE3A expression by downregulating UBE3A-ATS and relieving the epigenetic silencing of paternal UBE3A in mature neurons. (S)-PHA533533 can be used for the research of Angelman syndrome .
Synonyms: RG6091 sodium; RO7248824 sodium
Target:
Research Areas:
Rugonersen sodium is a locked-nucleic acid (LNA)- modified antisense oligonucleotides (ASOs), and results in reduction of ubiquitin-protein ligase E3A (UBE3A) silencing. Angelman syndrome (AS) sodium is a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, Rugonersen has been used for AS reasearch .
Cat. No.: HY-177615A
Synonyms: GTX-102 sodium
Target:
Research Areas:
Apazunersen sodium is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient
Cat. No.: HY-177615
CAS No.: 2919324-01-7
Synonyms: GTX-102
Target:
Research Areas:
Apazunersen is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient protei
Cat. No.: HY-RS15368
Target:
Research Areas:
UBE3A Human Pre-designed siRNA Set A contains three designed siRNAs for UBE3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20508
Target:
Research Areas:
Ube3a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube3a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177651
CAS No.: 2834724-31-9
Synonyms: ION-582
Target:
Research Areas:
Obudanersen is an antisense oligonucleotide targeted to ubiquitin protein ligase E3A-antisense transcript (UBE3A-ATS). It is used for the study of Angelman syndrome.
Cat. No.: HY-W001194
CAS No.: 5908-62-3
Synonyms: 1,1-Dioxoisothiazolidine
Research Areas:
1,3-Propanesultam (1,1-Dioxoisothiazolidine) is a cyclic sulfonamide monomer. Polymerization of 1,3-Propanesultam under base catalysis produces high-molecular-weight polypropanesulfonamide, while polymerization under acid catalysis yields low-molecular-weight polypropanesulfonamide. 1,3-Propanesultam serves as a coupling partner in copper-catalyzed C-N cross-coupling reactions for the synthesis of 3-aminopyrazole phenylacetamide analogs. 1,3-Propanesultam is applicable to research related to organic synthesis .
Cat. No.: HY-RS27016
Target:
Research Areas:
Ube3a Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube3a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177651A
Synonyms: ION-582 sodium
Target:
Research Areas:
Obudanersen sodium is an antisense oligonucleotide targeted to ubiquitin protein ligase E3A-antisense transcript (UBE3A-ATS). It is used for the study of Angelman syndrome.
Cat. No.: HY-P703594
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: E6AP; EPVE6AP; HPVE6A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
