![D[LEU4,LYS8]-VP TFA](https://file.medchemexpress.com/product_pic/hy-p1163a.gif "Click to View D[LEU4,LYS8]-VP TFA Product Detail")
![d[Cha4]-AVP](https://file.medchemexpress.com/product_pic/hy-p1390.gif "Click to View d[Cha4]-AVP Product Detail")
![D[LEU4,LYS8]-VP](https://file.medchemexpress.com/product_pic/hy-p1163.gif "Click to View D[LEU4,LYS8]-VP Product Detail")
![d[Cha4]-AVP TFA](https://file.medchemexpress.com/product_pic/hy-p1390a.gif "Click to View d[Cha4]-AVP TFA Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
V1b
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "V1b" in MCE Product Catalog:
1
Target:
Research Areas:
Nelivaptan (SSR-149415) is a selective and orally active vasopressin V1b receptor antagonist (Ki: 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Nelivaptan inhibits arginine vasopressin (AVP)-induced Ca 2+ increase and corticotropin secretion. Nelivaptan can be used for research of stress, anxiety and depression [1] .
Cat. No.: HY-P2657
CAS No.: 138067-14-8
Research Areas:
Target:
Research Areas:
SRX246 is a potent, BBB-penetrant, highly selective vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders [1].
Cat. No.: HY-P1163A
Target:
Research Areas:
Cat. No.: HY-P1390
CAS No.: 500170-27-4
Target:
Research Areas:
Target:
Research Areas:
TASP0390325 is a high affinity and orally active arginine vasopressin receptor 1B (V1B receptor) antagonist with antidepressant and anxiolytic activities [1].
Cat. No.: HY-178573
CAS No.: 1056550-56-1
Target:
Research Areas:
V1b receptor antagonist-1 is a potent, selective and brain-penetrant vasopressin 1b (V1b) receptor antagonist. V1b receptor antagonist-1 exhibits anti-depressant activity. V1b receptor antagonist-1 can be used for the research of neurological disease, such as depression [1].
Cat. No.: HY-RS01225
Target:
Research Areas:
ATP6V1B2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1163
CAS No.: 42061-33-6
Target:
Research Areas:
Cat. No.: HY-P0049A
CAS No.: 75499-44-4
Synonyms: Arg8-vasopressin diacetate; AVP diacetate; ADH
Target:
Research Areas:
Cat. No.: HY-P1390A
Target:
Research Areas:
Cat. No.: HY-P1737
CAS No.: 111317-90-9
Synonyms: Con-S
Target:
Research Areas:
Cat. No.: HY-120247
CAS No.: 1520893-08-6
Target:
Research Areas:
TASP0434299 (Compound 10) is a labeled ligand for the vasopressin V1b receptor. TASP0434299 exhibits high binding affinity for human and murine V1B receptors, with IC50 values of 0.526 nM and 0.641 nM, respectively, and shows potent antagonistic activity against the human V1B receptor with an IC50 of 0.639 nM. TASP0434299 is a substrate for human and rhesus monkey P-glycoprotein, resulting in low brain uptake in rhesus monkeys. TASP0434299 binds to V1B receptors in rat and monkey pituitary tissues in a saturable and specific manner both in vitro and in vivo. When radiolabeled with tritium or 11C, TASP0434299 serves as a prototype V1B receptor radiotracer to visualize V1B receptor in the pituitary gland of anesthetized monkeys via positron emission tomography [1] .
Cat. No.: HY-118918
CAS No.: 387816-81-1
Target:
Research Areas:
YM218 free base is an orally active non-peptide vasopressin (AVP) receptor antagonist. YM218 free base has a high affinity for rat liver V1A receptors with a Ki value of 0.50 nM; it has a lower affinity for rat pituitary V1B, kidney V2, and uterine oxytocin receptors with Ki values of 1510 nM, 72.2 nM, and 150 nM, respectively. YM218 free base can be used in the study of diabetes and kidney disease [1].
Cat. No.: HY-RS01224
Target:
Research Areas:
ATP6V1B1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-105685R
CAS No.: 512784-93-9
Research Areas:
SRX246 (Standard) is the analytical standard of SRX246 (HY-105685). This product is intended for research and analytical applications. SRX246 is a potent, BBB-penetrant, highly selective vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders [1].
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
