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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
Vascular endothelial growth factor C
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "Vascular endothelial growth factor C" in MCE Product Catalog:
7
7 Cited Publications
Cat. No.: HY-P74474
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFC; Vascular endothelial growth factor C; Vascular endothelial growth factor-Related Protein; VRP; VEGF-C; Flt4 Ligand; Flt4-L; FLT4 Ligand DHM; LMPH1D; LMPHM4
Species:
Mouse
Rat
Source:
HEK293
4
4 Cited Publications
Research Areas:
Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction .
3
3 Cited Publications
Cat. No.: HY-P7313
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFC; Vascular endothelial growth factor C; Vascular endothelial growth factor-Related Protein; VRP; VEGF-C; Flt4 Ligand; Flt4-L; FLT4 Ligand DHM; LMPH1D; LMPHM4
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-N0249
CAS No.: 20736-08-7
Target:
2
2 Cited Publications
Cat. No.: HY-P70458A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFA; Vascular endothelial growth factor A; VEGF; VPF; Vascular Permeability factor; Vascular endothelial growth factor A, Long Form; VEGF-A; L-VEGF; Vascular endothelial growth factor A121; Vascular endothelial growth factor A165; Vascular endothelial growth factor; VEGFA Protein; MVCD1
Species:
Human
Source:
HEK293
Synonyms: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
Category:
Cardiovascular Disease Animals Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-18711
CAS No.: 1174161-69-3
Synonyms: Metatinib free base; c-Met inhibitor 2 free base
Target:
Research Areas:
SCR-1481B1 free base, also known as Metatinib free base, is a small molecule receptor kinase inhibitor that targets both c-MET and vascular endothelial growth factor receptor 2 (VEGFR2) .
Cat. No.: HY-177134
CAS No.: 2243235-80-3
Target:
Research Areas:
Taligantinib (Compound Example 70) is an orally active and selective dual inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR-2) and hepatocyte growth factor receptor (c-Met). Taligantinib suppresses tumor angiogenesis and cell proliferation. Taligantinib is promising for research of solid tumors such as non-small cell lung cancer and hepatocellular carcinoma .
Cat. No.: HY-10338A
CAS No.: 1226999-07-0
Target:
Research Areas:
Foretinib phosphate is an orally bioavailable small molecule with potential anti-tumor activity. Foretinib phosphate can selectively inhibit hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), thereby potentially inhibiting tumor angiogenesis, tumor cell proliferation and metastasis. Foretinib phosphate shows different anti-cancer activity from cabozantinib in lung cancer cells and has stronger inhibitory effects on targets such as MEK1/2, FER and AURKB .
Cat. No.: HY-P10833
Cat. No.: HY-174507
Human VEGFD mRNA encodes the human vascular endothelial growth factor D (VEGFD) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is structurally and functionally similar to vascular endothelial growth factor C (VEGFC).
Cat. No.: HY-174508
Human VEGFC mRNA encodes the human vascular endothelial growth factor C (VEGFC) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFC promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels.
Cat. No.: HY-13718A
CAS No.: 237068-57-4
Synonyms: H-Glu-Trp-OH disodium; L-Glutamyl-L-tryptophan disodium
Target:
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
Oglufanide (H-Glu-Trp-OH) disodium is a dipeptide immunomodulator isolated from calf thymus. Oglufanide disodium inhibits vascular endothelial growth factor (VEGF). Oglufanide disodium can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide disodium shows antitumor and anti-angiogenesis activities .
Cat. No.: HY-15651S
Synonyms: AZD9668-13C,d3
Cat. No.: HY-15334
CAS No.: 402857-39-0
CEP-5214, derived from a new indenopyrrolocarbazole template, is a potent inhibitor of vascular endothelial growth factor R2 (VEGF-R2) tyrosine kinase. Structurally, it features optimal substitutions at positions 9 (ethoxymethyl) and 12 (hydroxypropyl) on the indeno[2,1-a]pyrrolo[3,4-c]carbazole-5-one scaffold, leading to high potency against VEGF-R2 (IC50 8 nM). Compound 21 (CEP-5214) exhibits low-nanomolar inhibition of human VEGF-R tyrosine kinases (IC50 4 nM for VEGF-R2/KDR), with good selectivity over other kinases. The compound demonstrated significant cellular and in vivo antitumor activity across various models and advanced into phase I clinical trials as a water-soluble prodrug (CEP-7055) to enhance oral bioavailability .
Cat. No.: HY-P706195
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFA; Vascular endothelial growth factor A; VEGF; VPF; Vascular Permeability factor; Vascular endothelial growth factor A, Long Form; VEGF-A; L-VEGF; Vascular endothelial growth factor A121; Vascular endothelial growth factor A165; Vascular endothelial growth factor; VEGFA Protein; MVCD1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
