1 Result for "

WELV

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "WELV" in MCE Product Catalog:

Procumbenoside I
Procumbenoside I
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Cat. No.: HY-N21657
CAS No.: 2243471-10-3
Category:  

Acanthaceae Extract Conioselinum smithii (H. Wolff) Pimenov & Kljuykov Lignans Phenylpropanoids Plants

Target:  

VSV SARS-CoV Influenza Virus Arenavirus

Procumbenoside I is a naturally derived broad-spectrum antiviral agent targeting the SFTSV glycoprotein Gn. Procumbenoside I binds to the conserved B domain of SFTSV Gn, blocking the binding and internalization steps during viral entry. Procumbenoside I inhibits the entry of VSV, H5N1, and SARS-CoV-2 pseudoviral particles, while exhibiting antiviral activity against bunyaviruses such as LCMV and WELV. Procumbenoside I protects mice against lethal SFTSV challenge, reducing mortality and alleviating pathological damage. Procumbenoside I is useful for research related to viral infections .
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