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Results for "

ZIKV E protein

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Inhibitory Antibodies

10

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161804
    GNF-2-deg

    		PROTACs Dengue Virus Infection
    GNF-2-deg is a PROTAC degrader for dengue virus envelope protein (DENV E protein) with DC50 of 0.83 μM. GNF-2-deg prevents viral entry by inhibiting E-mediated membrane fusion, prevents virion production by protein degradation, and thereby exhibits antiviral activity against DENV 2 with EC90 of 3.5 μM. GNF-2-deg exhibits antiviral activity against ZIKV, JEV, WNV and YFV with EC90 of 1.96-7.79 μM. (Pink: ligand for target protein (HY-161805); Black: linker (HY-42149); Blue: ligand for E3 ligase (HY-23095))
    GNF-2-deg
  • HY-176433
    NSC-323241

    		Flavivirus Infection
    NSC-323241 is a potent STT3A-mediated mega protein complex assembly inhibitor. NSC-323241 disrupts he endoplasmic reticulum (ER) mega complex nucleated by STT3A during dengue virus (DENV) and Zika virus (ZIKV) infection. NSC-323241 targets the binding of STT3A subcomplex with viral nonstructural proteins (e.g., NS2B, NS3) and host translocon proteins, disrupting the formation of viral replication microenvironment. NSC-323241 is promising for research of flavivirus infection, such as dengue fever and Zika virus .
    NSC-323241
  • HY-146957
    ZIKV-IN-1

    		Virus Protease Flavivirus Cancer
    ZIKV-IN-1 is a potent zika virus inhibitor with an EC50 of 2.8 μM and EC90 of 6.8 μM. ZIKV-IN-1 shows anti-ZIKV activity with low cytotoxicity. ZIKV-IN-1 shows a strong affinity to ZIKV RdRp domain . ZIKV-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    ZIKV-IN-1
  • HY-P991770
    Anti-Zika virus E protein DIII-LR Antibody (ZV-67)

    		Flavivirus Infection
    Anti-Zika virus E protein DIII-LR Antibody (ZV-67) reacts with Zika virus envelope (E) protein at the lateral ridge of domain III (DIII-LR). Anti-Zika virus E protein DIII-LR Antibody (ZV-67) specifically detects the recombinant ZIKV E protein DIII and ZIKV E protein reporter virus particles (RVPs) in transfected cells. Recommend Isotype Controls: Mouse IgG2c kappa, Isotype Control (HY-P99981) .
    Anti-Zika virus E protein DIII-LR Antibody (ZV-67)

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