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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
ZSH2117
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "ZSH2117" in MCE Product Catalog:
Cat. No.: HY-174415
ZSH-2117 is a covalent and selective EGFR PROTAC degrader with a DC50 of 45 nM in Ba/F3-EGFR L858R/T790M/C797S cells. ZSH-2117 significantly inhibits cell proliferation and reduces the downstream EGFR signaling proteins level of AKT and ERK. ZSH-2117 effectively inhibits tumor growth in Ba/F3-EGFR L858R/T790M/C797S xenograft mice model .
Cat. No.: HY-175162
Research Areas:
EGFR ligand-20 is a EGFR-binding ligand that serves as a target protein ligand for ZSH-2117 (HY-174415) and is used in studies related to PROTAC synthesis .
Cat. No.: HY-175159
CAS No.: 2223101-36-6
Target:
Research Areas:
3-Phenyl-2H-azirine-2-carboxylic acid is an E3 ubiquitin ligase ligand that can be used in studies related to PROTAC synthesis, such as ZSH-2117 (HY-174415) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
