4 Results for "

adipocyte development

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "adipocyte development" in MCE Product Catalog:

Sennidin B
Sennidin B
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Cat. No.: HY-N6935
CAS No.: 517-44-2
Category:  

Metabolic Disease Leguminosae Extract Plants Other Families Extract Infection Ketones, Aldehydes, Acids Phenols Polyphenols Cassia angustifolia Disease Research Fields

Target:  

Insecticide Dipeptidyl Peptidase PI3K Akt Endogenous Metabolite

Sennidin B is an anthraquinone compound isolated from Cassia angustifolia. Sennidin B is a DPP-4 inhibitor with an IC50 of 39.39 μM. Sennidin B is an insect chitinase inhibitor with a Ki of 80 nM against OfChi-h. Sennidin B competitively inhibits chitinase activity by forming π-π stacking interactions with key tryptophan residues in the active site through a folded conformation. Sennidin B activates PI3K/Akt to promote glucose uptake in adipocytes. Sennidin B can be used for the development of biopesticides and research on type 2 diabetes and metabolism-related signaling pathways .
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Sennidin B (Standard)
Sennidin B (Standard)
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Cat. No.: HY-N6935R
CAS No.: 517-44-2
Category:  

Ketones, Aldehydes, Acids Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia Other Families Extract

Target:  

Reference Standards Insecticide Dipeptidyl Peptidase PI3K Akt Endogenous Metabolite

Sennidin B Standard is the analytical standard of Sennidin B (HY-N6935). This product is intended for research and analytical applications. Sennidin B is an anthraquinone compound isolated from Cassia angustifolia. Sennidin B is a DPP-4 inhibitor with an IC50 of 39.39 μM. Sennidin B is an insect chitinase inhibitor with a Ki of 80 nM against OfChi-h. Sennidin B competitively inhibits chitinase activity by forming π-π stacking interactions with key tryptophan residues in the active site through a folded conformation. Sennidin B activates PI3K/Akt to promote glucose uptake in adipocytes. Sennidin B can be used for the development of biopesticides and research on type 2 diabetes and metabolism-related signaling pathways .
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ATS-9R
ATS-9R
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Cat. No.: HY-P11612
Target:  

Biochemical Assay Reagents

연구분야:  

Metabolic Disease

ATS-9R is a peptide consisting of an adipocyte-targeting sequence and D-form 9-arginine. ATS-9R selectively transfects mature adipocytes by binding to prohibitin. ATS-9R allows an adipocyte-targeted gene delivery in vitro and in vivo. ATS-9R can be used for the development of an adipocyte-targeted gene carrier. ATS-9R can be used for the study of obesity as well as obesity-induced metabolic syndromes .
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CM002
CM002
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Cat. No.: HY-184895
Target:  

Cryptochrome REV-ERB Nuclear Hormone Receptor 4A/NR4A FABP PARP Fatty Acid Synthase (FASN) Wnt β-catenin Hormone-Sensitive Lipase (HSL) PGC-1α ROR GLUT

연구분야:  

Metabolic Disease

CM002 is a circadian clock activator. CM002 inhibits the lineage commitment and terminal differentiation of preadipocytes by activating the circadian clock, thereby blocking the adipogenesis process driven by Wnt signaling-mediated transcriptional induction. CM002 attenuates lipid storage in a clock-dependent manner via inhibition of the lipogenic program in mature adipocytes. CM002 enhances circadian clock output across various adipose depots in both lean and obese mice through BMAL1/CLOCK-dependent metabolic reprogramming, inhibits adipocyte development and hypertrophy, and improves insulin sensitivity. CM002 can be used in research on obesity and type 2 diabetes .
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