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Results for "

aromatic polyketide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Bacterial (1) Endogenous Metabolite (1) Interleukin Related (1) Nuclear Factor of activated T Cells (NFAT) (1)
By Research Areas:	Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Citromycetin	Bacterial	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

NFAT-133	AMPK Nuclear Factor of activated T Cells (NFAT) Interleukin Related Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
NFAT-133 is an aromatic polyketide with immunosuppressive and antidiabetic activity. NFAT-133 activates the AMPK pathway, promoting glucose uptake in L6 muscle fibers, thereby resisting diabetes. NFAT-133 inhibits the transcriptional activity of activated T-cell nuclear factor (NFAT), thereby suppressing the expression of IL-2 and the proliferation of T cells, demonstrating an immunosuppressive effect. NFAT-133 does not exhibit antibacterial activity or cytotoxicity, but it can weaken the production of NO in RAW264.7 cells induced by Lipopolysaccharide (LPS) (HY-D1056) .

Tetracenomycin X	Others	Infection
Tetracenomycin X is a natural aromatic polyketide compound. Tetracenomycin X can inhibit peptide bond formation between an incoming aminoacyl-tRNA and a terminal Gln-Lys (QK) motif in the nascent polypeptide. Tetracenomycin X can be used for the development of novel aromatic polyketide antibiotics .

Citromycetin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Other Diseases Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	Bacterial
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

NFAT-133	Natural Products Microorganisms Source Classification	AMPK Nuclear Factor of activated T Cells (NFAT) Interleukin Related Endogenous Metabolite
NFAT-133 is an aromatic polyketide with immunosuppressive and antidiabetic activity. NFAT-133 activates the AMPK pathway, promoting glucose uptake in L6 muscle fibers, thereby resisting diabetes. NFAT-133 inhibits the transcriptional activity of activated T-cell nuclear factor (NFAT), thereby suppressing the expression of IL-2 and the proliferation of T cells, demonstrating an immunosuppressive effect. NFAT-133 does not exhibit antibacterial activity or cytotoxicity, but it can weaken the production of NO in RAW264.7 cells induced by Lipopolysaccharide (LPS) (HY-D1056) .

Tetracenomycin X	Structural Classification Natural Products Microorganisms Source Classification	Others
Tetracenomycin X is a natural aromatic polyketide compound. Tetracenomycin X can inhibit peptide bond formation between an incoming aminoacyl-tRNA and a terminal Gln-Lys (QK) motif in the nascent polypeptide. Tetracenomycin X can be used for the development of novel aromatic polyketide antibiotics .

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