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United States

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Cat. No.: HY-N13141

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Tetracenomycin X

Tetracenomycin X is a natural aromatic polyketide compound. Tetracenomycin X can inhibit peptide bond formation between an incoming aminoacyl-tRNA and a terminal Gln-Lys (QK) motif in the nascent polypeptide. Tetracenomycin X can be used for the development of novel aromatic polyketide antibiotics .

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CAS No.: 121245-07-6
화학식: C₂₄H₂₂O₁₁
분자량:486.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tetracenomycin X Chemical Structure

CAS No.: 121245-07-6

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	1.6 μM Compound: Tetracenomycin X	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay	[PMID: 26317881]
K562	IC₅₀	5.2 μM Compound: Tetracenomycin X	Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay	[PMID: 26317881]
MCF7	IC₅₀	1.5 μM Compound: Tetracenomycin X	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay	[PMID: 26317881]

Chemical Information

CAS No. 121245-07-6
분자량 486.42
화학식 C₂₄H₂₂O₁₁
SMILES

CO[C@@]12[C@@](C(C(C(C1=O)=C(C3=C4C)O)=CC3=CC(OC)=C4C(OC)=O)=O)([C@@H](C(OC)=CC2=O)O)O
Structure Classification
- Others
Initial Source
- Microorganisms
Saccharothrix sp.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leroy EC, et al. Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs. Nat Chem Biol. 2023 Sep;19(9):1091-1096. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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