Search Result
Results for "
biotin ligand
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-D1056F
-
|
biotin-LPS, from Escherichia coli (O111:B4)
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
Biotin-Lipopolysaccharide, from E.coli O111:B4 (Biotin-LPS, from Escherichia coli (O111:B4)) is a biotin-conjugated Lipopolysaccharide (LPS) (HY-D1056A1) that can be coupled with streptavidin protein. Biotin-Lipopolysaccharide, from E.coli O111:B4 can be used to identify Lipopolysaccharide ligands. Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. Lipopolysaccharides, from E. coli O111:B4 can also induce M1-type polarization in mouse macrophages .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
|
-
-
- HY-147102
-
|
|
LYTACs
|
Metabolic Disease
|
|
tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. tri-GalNAc biotin promotes cellular uptake of neutravidin (NA) via ASGPR. tri-GalNAc biotin delivers neutravidin to lysosomes for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC) .
|
-
-
- HY-W1048661E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG2000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG2000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-150741A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-W1048661A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG5000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-W1048661
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG1000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG1000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-N0437F
-
|
Pregn-4-ene-3,20-dione-biotin
|
Progesterone Receptor
Drug Derivative
|
Cardiovascular Disease
Cancer
|
|
Progesterone 3-biotin (Pregn-4-ene-3,20-dione-biotin) is a biotin-labeled probe that allows progesterone to be detected or immobilized using the biotin ligand. Progesterone 3-biotin is the biotinylated derivative of Progesterone (HY-N0437) .
|
-
-
- HY-P4863
-
|
|
CGRP Receptor
|
Neurological Disease
Metabolic Disease
|
|
Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .
|
-
-
- HY-111879
-
|
|
SNIPERs
|
Cancer
|
|
Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
|
-
-
- HY-W1048661H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG3400-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG3400-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-145502
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .
|
-
-
- HY-175147
-
-
-
- HY-113331F
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Thromboxane B2-biotin is an affinity probe that allows detection of thromboxane B2 through an interaction with the biotin ligand. Thromboxane B2-biotin is designed to allow thromboxane B2 to be detected in complexes with protein binding partners .
|
-
-
- HY-172666F
-
|
biotin ceramide (d18:0/6:0)
|
Fluorescent Dye
|
Neurological Disease
|
|
C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
|
-
-
- HY-175142
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Prostaglandin E2-PEG11-biotin is a ligand. Prostaglandin E2-PEG11-biotin can be immobilized on flow cells. The immobilized Prostaglandin E2-PEG11-biotin binds to BtOCT1. Prostaglandin E2-PEG11-biotin can be used in SPR .
|
-
-
- HY-D3303
-
|
8-iso PGA2-biotin
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
8-iso Prostaglandin A2-biotin (8-iso PGA2-biotin) is an affinity probe conjugated with biotin, consisting of 8-iso Prostaglandin A2 (8-iso PGA2). 8-iso PGA2 is an isoprostaglandane produced by the radical-catalyzed peroxidation of arachidonic acid. 8-iso Prostaglandin A2-biotin can be detected by its interaction with a biotin ligand .
|
-
-
- HY-175133
-
|
biotin ceramide (t18:0/6:0)
|
Fluorescent Dye
|
Others
|
|
C6 Biotin phytoceramide (t18:0/6:0) is an affinity probe that allows C6 phytoceramide to be detected or immobilized through interaction with the biotin ligand .
|
-
-
- HY-173643
-
|
biotin-C6:0-gm3 ammonium; N-Hexanoyl-biotin-monosialoganglioside gm3 ammonium
|
Drug Derivative
|
Metabolic Disease
|
|
C6 Biotin ganglioside gm3 (d18:1/6:0) (Biotin-C6:0-gm3) ammonium is a derivative of ganglioside GM3. C6 Biotin ganglioside gm3 (d18:1/6:0) ammonium can be used to detect or immobilize ganglioside GM3 through interaction with the biotin ligand .
|
-
-
- HY-W130607
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotinyl-8-amino-3,6-dioxaoctanoic acid is a biotinylating reagent linked with a PEG chain for improved water solubility. Biotin is an affinity ligand and it is used in biochemical applications such as pull-down assays or for ligating with streptavidin proteins. The carboxylic group can react with amine-containing molecules in the presence of activators such as HATU.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-175147
-
|
|
Fluorescent Dyes
|
|
Progesterone 3-PEG11-biotin is an affinity probe. Progesterone 3-PEG11-biotin allows progesterone to be detected or immobilized using the biotin ligand.
|
-
- HY-172666F
-
|
biotin ceramide (d18:0/6:0)
|
Fluorescent Dyes
|
|
C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
|
-
- HY-175142
-
|
|
Fluorescent Dyes
|
|
Prostaglandin E2-PEG11-biotin is a ligand. Prostaglandin E2-PEG11-biotin can be immobilized on flow cells. The immobilized Prostaglandin E2-PEG11-biotin binds to BtOCT1. Prostaglandin E2-PEG11-biotin can be used in SPR .
|
-
- HY-D3303
-
|
8-iso PGA2-biotin
|
Fluorescent Dyes
|
|
8-iso Prostaglandin A2-biotin (8-iso PGA2-biotin) is an affinity probe conjugated with biotin, consisting of 8-iso Prostaglandin A2 (8-iso PGA2). 8-iso PGA2 is an isoprostaglandane produced by the radical-catalyzed peroxidation of arachidonic acid. 8-iso Prostaglandin A2-biotin can be detected by its interaction with a biotin ligand .
|
-
- HY-175133
-
|
biotin ceramide (t18:0/6:0)
|
Fluorescent Dyes
|
|
C6 Biotin phytoceramide (t18:0/6:0) is an affinity probe that allows C6 phytoceramide to be detected or immobilized through interaction with the biotin ligand .
|
-
- HY-173643
-
|
biotin-C6:0-gm3 ammonium; N-Hexanoyl-biotin-monosialoganglioside gm3 ammonium
|
Fluorescent Dyes
|
|
C6 Biotin ganglioside gm3 (d18:1/6:0) (Biotin-C6:0-gm3) ammonium is a derivative of ganglioside GM3. C6 Biotin ganglioside gm3 (d18:1/6:0) ammonium can be used to detect or immobilize ganglioside GM3 through interaction with the biotin ligand .
|
| Cat. No. |
Product Name |
Type |
-
- HY-D1056F
-
|
biotin-LPS, from Escherichia coli (O111:B4)
|
Biochemical Assay Reagents
|
Biotin-Lipopolysaccharide, from E.coli O111:B4 (Biotin-LPS, from Escherichia coli (O111:B4)) is a biotin-conjugated Lipopolysaccharide (LPS) (HY-D1056A1) that can be coupled with streptavidin protein. Biotin-Lipopolysaccharide, from E.coli O111:B4 can be used to identify Lipopolysaccharide ligands. Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. Lipopolysaccharides, from E. coli O111:B4 can also induce M1-type polarization in mouse macrophages .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
|
-
- HY-W1048661E
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG2000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG2000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661A
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG5000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG1000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG1000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661H
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG3400-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG3400-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4863
-
|
|
CGRP Receptor
|
Neurological Disease
Metabolic Disease
|
|
Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-150741A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-145502
-
|
|
|
Phospholipids
|
|
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
