6 Results for "

bone-protective

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "bone-protective" in MCE Product Catalog:

8
8 Publications Verification
製品番号: HY-19322B
CAS 番号: 1820565-69-2
別名: LGH447 dihydrochloride
Target:  

Pim Apoptosis

研究分野:  

Cancer

PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis .
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8
8 Publications Verification
製品番号: HY-19322
CAS 番号: 1210608-43-7
別名: LGH447
Target:  

Pim Apoptosis

研究分野:  

Cancer

PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis .
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5
5 Cited Publications
製品番号: HY-10003
CAS 番号: 41294-56-8
純度:  99.96%
別名: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3
研究分野:  

Metabolic Disease

Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis .
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製品番号: HY-N0616
CAS 番号: 6807-83-6
Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC50 value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .
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製品番号: HY-10003R
CAS 番号: 41294-56-8
別名: 1-hydroxycholecalciferol (Standard); 1.alpha.-Hydroxyvitamin D3 (Standard)
研究分野:  

Metabolic Disease

Alfacalcidol (Standard) is the analytical standard of Alfacalcidol. This product is intended for research and analytical applications. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis .
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製品番号: HY-169953
Target:  

Pyk2

研究分野:  

Metabolic Disease

BT-Amide is the orally active inhibitor for Pyk2 kinase with IC50 of 44.69 nM. BT-Amide prevents glucocorticoid-induced bone loss, exhibits bone protective activity in C57BL/6 mouse .
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