8 Results for "

c8161

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "c8161" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-111793
CAS No.: 1060524-97-1
Purity:  98.40%
Target:  

CXCR

Research Areas:  

Neurological Disease

NUCC-390 is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046) . NUCC-390 promotes nerve recovery of function after neurodegeneration in vivo .
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6
6 Publications Verification
Cat. No.: HY-111793A
CAS No.: 2749281-71-6
Purity:  98.19%
Target:  

CXCR

Research Areas:  

Neurological Disease

NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 dihydrochloride induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046) . NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo .
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4
4 Cited Publications
Cat. No.: HY-12855A
CAS No.: 1391426-24-6
Purity:  99.89%
Synonyms: Lys01 trihydrochloride
Target:  

Autophagy

Research Areas:  

Cancer

Lys05 (Lys01 trihydrochloride) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
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Cat. No.: HY-P4091
CAS No.: 945245-76-1
Research Areas:  

Cancer

LSD is a peptide. LSD can specifically recognize the lymphatics of C8161 melanoma, but it does not bind to the lymphatics of normal tissues or tumor blood vessels. When conjugated with a proapoptotic peptide, LSD can reduce the number of tumor lymphatics. LSD can be used in the research of targeted therapy and diagnosis of tumor lymphatics .
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Cat. No.: HY-P4088
CAS No.: 850859-24-4
Target:  

Peptides

Research Areas:  

Cancer

LyP-2 is a peptide that homes to tumor lymphatics. LyP2 homes to lymphatics of C8161 melanomas and cervical carcinomas and K14-HPV16 skin, but not to MDA-MB435 tumors, showing heterogeneity in the molecular markers of tumor cells and lymphatics .
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Cat. No.: HY-P4091A
Research Areas:  

Cancer

LSD acetate is a peptide. LSD acetate can specifically recognize the lymphatics of C8161 melanoma, but it does not bind to the lymphatics of normal tissues or tumor blood vessels. When conjugated with a proapoptotic peptide, LSD acetate can reduce the number of tumor lymphatics. LSD acetate can be used in the research of targeted therapy and diagnosis of tumor lymphatics .
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Cat. No.: HY-12855
CAS No.: 1391426-22-4
Target:  

Autophagy

Research Areas:  

Cancer

Lys01, a dimeric form of Chloroquine (HY-17589A), is an autophagy inhibitor. Lys01 inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 μM. Lys01 can be used for anticancer research .
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Cat. No.: HY-164400
CAS No.: 839707-55-0
Target:  

MEK ERK Akt Apoptosis

Research Areas:  

Cancer

SIJ1777 is a GNF-7 (HY-10943) derivative, possesses potent anti-cancer effects on melanoma cells harboring BRAF class I/II/III mutations. SIJ1777 substantially inhibits the activation of MEK, ERK, and AKT. SIJ1777 remarkably induces apoptosis and significantly blocks migration, invasion, and anchorage-independent growth of melanoma cells harboring BRAF class I/II/II mutations .
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