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callus culture

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By Targets:	Bacterial (1) Endogenous Metabolite (2) Fungal (1) Interleukin Related (1) Nucleoside Antimetabolite/Analog (1) Reference Standards (1) TNF Receptor (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112642

9-Methoxycanthin-6-one	TNF Receptor	Cancer
9-Methoxycanthin-6-one, a canthin-6-one alkaloid, is present in intact plant parts and in callus tissues of different explants. 9-Methoxycanthin-6-one shows anti-tumor activity, inhibits LPS-induced TNF-α and IL-1β .

HY-N0902

Dihydrosanguinarine 13,14-Dihydrosanguinarine	Fungal Bacterial Interleukin Related	Infection Inflammation/Immunology
Dihydrosanguinarine (13,14-Dihydrosanguinarine) is an alkaloid with antibacterial and anti-inflammatory activities, and also an important precursor of Sanguinarine (HY-N0052). Dihydrosanguinarine targets and regulates the TNF/IL-17/PI3K signaling pathway, downregulates the levels of pro-inflammatory factors such as IL-17A, TNF-α and IL-6, upregulates the expression of TGF-β, inhibits myeloperoxidase activity, and regulates the transcription of multiple inflammation-related genes. Dihydrosanguinarine exhibits antibacterial activity against a variety of oral microorganisms. Dihydrosanguinarine can be used in research related to liver inflammation and oral flora dysbiosis .

HY-N16520

Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate)	Others	Others
Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate) is an acylated flavonol glycoside. Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate) can be isolated from 10-year-old callus cultures of Mexican lime .

HY-N1753

3-(4-Hydroxyphenyl)-1-propanol Dihydro-p-coumaryl alcohol; 3-(p-Hydroxyphenyl)propyl alcohol	Endogenous Metabolite	Others
3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .

HY-N9815

Leontopodic acid B	Others	Others
Leontopodic acid B is a phenylpropanoid found in Leontopodium alpinum callus culture extract (LACCE) .

HY-N1753R

3-(4-Hydroxyphenyl)-1-propanol (Standard) Dihydro-p-coumaryl alcohol (Standard); 3-(p-Hydroxyphenyl)propyl alcohol (Standard)	Reference Standards Endogenous Metabolite	Others
3-(4-Hydroxyphenyl)-1-propanol (Standard) is an analytical standard of 3-(4-Hydroxyphenyl)-1-propanol (HY-N1753). This product is intended for research and analytical applications. 3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .

HY-180756

p-Coumaroylputrescine	Nucleoside Antimetabolite/Analog	Others
p-Coumaroylputrescine is a product found in the callus tissue culture of Nicotiana tabacum .

HY-N9548

6'-Malonyltrifolirhizin Trifolirhizin 6''-O-malonate	Others	Others
6'-Malonyltrifolirhizin (Trifolirhizin 6''-O-malonate) is a malonylated pterocarpan glucoside that can be isolated both from the roots and callus cultures of Sophora flavescens var. angustifolia .

9-Methoxycanthin-6-one	Alkaloids other families Classification of Application Fields Plants Disease Research Fields Indole Alkaloids Source Classification Cancer	TNF Receptor
9-Methoxycanthin-6-one, a canthin-6-one alkaloid, is present in intact plant parts and in callus tissues of different explants. 9-Methoxycanthin-6-one shows anti-tumor activity, inhibits LPS-induced TNF-α and IL-1β .

Dihydrosanguinarine 13,14-Dihydrosanguinarine	Infection Alkaloids Structural Classification Classification of Application Fields Quinoline Alkaloids Macleaya cordata (Willd.) R. Br. Plants Disease Research Fields Papaveraceae Source Classification	Fungal Bacterial Interleukin Related
Dihydrosanguinarine (13,14-Dihydrosanguinarine) is an alkaloid with antibacterial and anti-inflammatory activities, and also an important precursor of Sanguinarine (HY-N0052). Dihydrosanguinarine targets and regulates the TNF/IL-17/PI3K signaling pathway, downregulates the levels of pro-inflammatory factors such as IL-17A, TNF-α and IL-6, upregulates the expression of TGF-β, inhibits myeloperoxidase activity, and regulates the transcription of multiple inflammation-related genes. Dihydrosanguinarine exhibits antibacterial activity against a variety of oral microorganisms. Dihydrosanguinarine can be used in research related to liver inflammation and oral flora dysbiosis .

Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate)	Structural Classification Monophenols Flavonoids Flavones Citrus × aurantiifolia (Christmann) Swingle Polygonaceae Rutaceae Phenols Euphorbiaceae Plants Polygonum tinctorium Ait. Source Classification	Others
Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate) is an acylated flavonol glycoside. Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate) can be isolated from 10-year-old callus cultures of Mexican lime .

Leontopodic acid B	Structural Classification Leontopodium brachyactis Gand. Asteraceae Phenols Polyphenols Plants Source Classification	Others
Leontopodic acid B is a phenylpropanoid found in Leontopodium alpinum callus culture extract (LACCE) .

p-Coumaroylputrescine	Structural Classification Monophenols Nicotiana tabacum L. Phenols Solanaceae Plants Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
p-Coumaroylputrescine is a product found in the callus tissue culture of Nicotiana tabacum .

6'-Malonyltrifolirhizin Trifolirhizin 6''-O-malonate	Structural Classification Flavonoids Leguminosae Sophora flavescens Aiton Plants Other Flavonoids Source Classification	Others
6'-Malonyltrifolirhizin (Trifolirhizin 6''-O-malonate) is a malonylated pterocarpan glucoside that can be isolated both from the roots and callus cultures of Sophora flavescens var. angustifolia .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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callus culture

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