Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
cholic acid derivative
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "cholic acid derivative" in MCE Product Catalog:
Category:
Human Gut Microbiota Metabolites other families Microorganisms Ketones, Aldehydes, Acids Marine natural products Metabolic Disease Plants Endogenous metabolite Disease Research Fields
Target:
Synonyms: Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG
Category:
Target:
Synonyms: 2-Hydroxyethanesulfonic acid sodium; Sodium isethionate
Target:
Cat. No.: HY-W585922
CAS No.: 3338-16-7
Target:
Research Areas:
3β-Cholic acid is a derivative of cholic acid (HY-N0324), and can be found in human feces .
Cat. No.: HY-174300
CAS No.: 95051-21-1
Target:
Research Areas:
Cholic acid-Glu is a derivative of Cholic acid (HY-N0324). The abundance of Cholic acid-Glu is increased in Crohn’s disease. Cholic acid-Glu increases PXR activation and significantly increases the expression of the downstream PXR target gene Cyp3a11 in small intestinal organoid tissue .
Cat. No.: HY-15435R
CAS No.: 75621-03-3
Target:
Research Areas:
CHAPS (Standard) is the analytical standard of CHAPS. This product is intended for research and analytical applications. CHAPS, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution .
Cat. No.: HY-155306
CAS No.: 2148317-51-3
Research Areas:
TGR5 agonist 3 (compound 8), a Cholic acid derivative, is a selective TGR5 agonist with an EC50 of 5 μM .
Cat. No.: HY-155307
Research Areas:
TGR5 agonist 4 (compound 19), a cholic acid derivative, is a selective TGR5 agonist with an EC50 of 4 μM .
Cat. No.: HY-113074R
CAS No.: 15324-64-8
Synonyms: Glycolithocholate sulfate (Standard); Sulfolithocholylglycine (Standard); SLCG (Standard)
Category:
Cat. No.: HY-W706341
CAS No.: 86992-52-1
Target:
Research Areas:
7,7-Azo-3-α,12-α-dihydroxycholanic acid is a photoinactive (photopolymerization) derivative of Cholic acid (HY-N0324), and it has a relatively low affinity for high-density lipoprotein (HDL) .
Target:
Research Areas:
3-aceCA is an orally active 3α-O-acetyl cholic acid derivative and monoacylated bile acid. 3-aceCA can be used for the study of gut microbiota-bile acid metabolism and metabolic dysfunction-associated steatohepatitis (MASH) .
Cat. No.: HY-180845
CAS No.: 2931879-67-1
Research Areas:
TGR5 agonist 9 is a highly selective and orally active TGR5 allosteric agonist with EC₅₀ values for hTGR5 and mTGR5 of 0.48 and 0.49 μM, respectively. TGR5 agonist 9 can recruit β-arrestin 1 (EC₅₀ = 78.8 μM) and β-arrestin 2 (EC₅₀ = 12.3 μM), and has a higher efficacy in cAMP accumulation (EC₅₀ = 0.48 μM). TGR5 agonist 9 exhibits a significant hypoglycemic effect in the ICR mouse model. TGR5 agonist 9 can be used for research on diabetes .
Synonyms: 2-Hydroxyethanesulfonic acid sodium (Standard); Sodium isethionate (Standard)
Category:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
