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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
coumarin moiety
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "coumarin moiety" in MCE Product Catalog:
Cat. No.: HY-76779
CAS No.: 25392-41-0
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4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
Cat. No.: HY-D3107
CAS No.: 1826900-73-5
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ER-Fluidity is a fluorescent probe used to detect the membrane fluidity of the endoplasmic reticulum (ER). ER-Fluidity consists of BODIPY, Coumarin (HY-N0709) moieties and a long-chain n-octadecyl group (n-C18). The excitation/emission wavelengths of the Coumarin moiety of ER-Fluidity are Ex/Em = 350/439 nm, while those of the BODIPY moiety are Ex/Em = 500/518 nm. In cell experiments, 488 nm is additionally used as an excitation wavelength for the BODIPY moiety .
Cat. No.: HY-D3007
Cat. No.: HY-D3521
CAS No.: 1807503-82-7
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Coumarin 343 azide is a fluorescent dye used for the fluorescent labeling of alkyne-containing biomolecules based on click chemistry. Its detection mechanism relies on the copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC), a type of click reaction: under mild aqueous conditions, the azide group of this dye selectively reacts with the alkyne moiety of propargyl geldanamycin to form a triazole bond that conjugates the fluorescent dye to the target biomolecule; fluorescence is generated upon successful conjugation to the target .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
