9 Results for "

cutaneous lupus erythematosus

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "cutaneous lupus erythematosus" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-134581
CAS No.: 2101938-42-3
Purity:  99.80%
Synonyms: M5049
Research Areas:  

Inflammation/Immunology

Enpatoran (M5049) is an orally active and selective TLR7/8 antagonist. Enpatoran inhibits the activation of the downstream type I interferon pathway. Enpatoran is used in studies of cutaneous lupus erythematosus, systemic lupus erythematosus with cutaneous manifestations, and psoriasis .
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18
18 Publications Verification
Cat. No.: HY-134581A
CAS No.: 2101945-93-9
Purity:  99.42%
Synonyms: M5049 hydrochloride
Research Areas:  

Inflammation/Immunology

Enpatoran hydrochloride (M5049 hydrochloride) is an orally active and selective TLR7/8 antagonist. Enpatoran hydrochloride inhibits the activation of the downstream type I interferon pathway. Enpatoran hydrochloride is used in studies of cutaneous lupus erythematosus, systemic lupus erythematosus with cutaneous manifestations, and psoriasis .
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Cat. No.: HY-145588
CAS No.: 1637677-22-5
Purity:  99.00%
Synonyms: INCB54707
Target:  

JAK

Research Areas:  

Inflammation/Immunology

Povorcitinib (INCB54707) is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib is used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) .
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Cat. No.: HY-P9990
CAS No.: 2407378-48-5
Synonyms: BIIB059
Litifilimab (BIIB059) is a humanized IgG1 monoclonal antibody targeting BDCA2. Litifilimab induces internalization of BDCA2 receptors on the membrane of plasmacytoid dendritic cells, inhibits the TLR7/TLR9 signaling pathway, and suppresses the production of type I interferons. Litifilimab can be used in the research of systemic and cutaneous lupus erythematosus .
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Cat. No.: HY-145588A
CAS No.: 1637677-33-8
Purity:  98.82%
Synonyms: INCB54707 phosphate
Target:  

JAK

Research Areas:  

Inflammation/Immunology

Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1) .
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Cat. No.: HY-115676
CAS No.: 2048226-46-4
Research Areas:  

Inflammation/Immunology

GSK199 analog hydrochloride belongs to a class of compounds that inhibit PAD4 (guanidinoarginine deiminase 4). GSK199 analog hydrochloride has potential uses in diseases including rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosus, and psoriasis .
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Cat. No.: HY-P991313

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology

PD-360324 is a human monoclonal antibody (mAb) targeting CSF1/M-CSF. PD-360324 can be used in cutaneous lupus erythematosus, pulmonary sarcoidosis and rheumatoid arthritis research .
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Cat. No.: HY-145588S
CAS No.: 3029304-24-0
Synonyms: INCB54707-d6
Povorcitinib-d6 (INCB54707-d6) is the deuterium labeled Povorcitinib (HY-145588). Povorcitinib (INCB54707) is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib is used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) .
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Cat. No.: HY-134581B
CAS No.: 2409589-21-3
Synonyms: M5049 dihydrochloride
Research Areas:  

Inflammation/Immunology

Enpatoran dihydrochloride (M5049 dihydrochloride) is an orally active and selective TLR7/8 antagonist. Enpatoran dihydrochloride inhibits the activation of the downstream type I interferon pathway. Enpatoran dihydrochloride is used in studies of cutaneous lupus erythematosus, systemic lupus erythematosus with cutaneous manifestations, and psoriasis .
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