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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
cyclic AMP (cAMP)
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "cyclic AMP (cAMP)" in MCE Product Catalog:
39
39 Publications Verification
Synonyms: 8-Br-CAMP sodium salt
8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells .
39
39 Publications Verification
Synonyms: 8-Br-CAMP
8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells .
30
30 Cited Publications
Synonyms: cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP
Category:
Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields
Target:
30
30 Cited Publications
Cat. No.: HY-B1511A
CAS No.: 37839-81-9
Synonyms: cyclic adenosine monophosphate sodium; Adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium
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2
1
1 Cited Publications
Cat. No.: HY-W040329
CAS No.: 958-09-8
1
1 Cited Publications
Cat. No.: HY-W011683
CAS No.: 16373-93-6
1
1 Cited Publications
Cat. No.: HY-P80486
Synonyms: CREB2, TXREB, ATF4, cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, cyclic AMP-responsive element-binding protein 2, Tax-responsive enhancer element-binding protein 67, CREB-2, cAMP-responsive element-binding protein 2, TaxREB67
Synonyms: 8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium
Target:
Research Areas:
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC50Cyclic AMP sodium is a very high affinity for Epac and is a potent Epac activator .
Cat. No.: HY-P0221C
CAS No.: 129405-61-4
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Research Areas:
Cat. No.: HY-B1511S
CAS No.: 2170095-23-3
Synonyms: cyclic adenosine monophosphate-13C5; Adenosine cyclic 3', 5'-monophosphate-13C5; cAMP-13C5
Synonyms: 2'-O-Monobutyryl cyclic AMP sodium
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Research Areas:
2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AMP) sodium is an inactive analog of Cyclic AMP. 2'-O-MB-cAMP sodium serves as a reference standard in FAB/MIKE mass spectrometry for the characterization of butyryl derivatives of cyclic nucleotides. 2'-O-MB-cAMP sodium does not induce differentiation or upregulate Nm23-R1 in glioma cells. 2'-O-MB-cAMP sodium can be used as a negative control cAMP analog for glioma-related research .
Cat. No.: HY-B0392
CAS No.: 85416-73-5
Synonyms: (+)-Rolipram; (S)-Rolipram
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Research Areas:
(S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells .
Synonyms: cyclic adenosine monophosphate (Standard); Adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)
Research Areas:
Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
Synonyms: Daxalipram
Research Areas:
Mesopram (Daxalipram) is an orally active phosphodiesterase (PDE) 4 inhibitor. Mesopram inhibits the synthesis of proinflammatory cytokines TNF-α and IFN-γ. Mesopram demonstrates efficacy in ameliorating Dextran sulfate sodium (DSS) (HY-116282C)-induced murine colitis. Mesopram can be used for the study of chronic inflammatory diseases .
Cat. No.: HY-107544
CAS No.: 1152197-23-3
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Research Areas:
8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway .
Research Areas:
AM-001 is a selective Epac1 inhibitor with an IC50 value of 47.8-53.7 μM. AM-001 blocks cAMP (Cyclic AMP) (HY-B1511)-induced conformational changes of Epac1, inhibits Epac1-dependent activation of Rap1, and does not compete with cAMP for binding to Epac1. AM-001 disrupts the formation of the Epac1-GRK5 complex, blocks nuclear import of GRK5, and inhibits GRK5-mediated nuclear export of HDAC5 and activation of MEF2. AM-001 can be used in research related to heart disease, myocardial ischemia/reperfusion injury, SARS-CoV-2 infection, influenza A virus infection, atrial fibrillation and idiopathic pulmonary fibrosis .
Cat. No.: HY-W040329R
CAS No.: 958-09-8
Cat. No.: HY-W040329S1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
