28 Results for "

cysteine-rich domain

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "cysteine-rich domain" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-12316
CAS No.: 516-72-3
Purity:  99.29%
Synonyms: 20α-Hydroxycholesterol
20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator that selectively targets the Smoothened (Smo) of the Hedgehog pathway with an EC50 of ~30 μM (Hedgehog). 20(S)-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo in a stereoselective manner, activating downstream Gli transcription factors (without inducing transcription of receptor genes in the Wnt pathway). 20(S)-Hydroxycholesterol enhances osteogenic differentiation of bone marrow stromal cells and synergistically activates the Raf/MEK/ERK pathway with Simvastatin (HY-17502) to promote bone regeneration. 20(S)-Hydroxycholesterol can be used to study the mechanisms of developmental biology, oncology, bone, and angiogenesis .
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Cat. No.: HY-162372
CAS No.: 2916444-33-0
Target:  

Hedgehog Smo

Research Areas:  

Cancer

Hedgehog IN-6 (Compound Q29) is a Hedgehog (Hh) inhibitor that can be used in cancer research. Hedgehog IN-6 inhibits the hedgehog (Hh) pathway by binding to the cysteine-rich domain (CRD) of Smoothened (Smo) and blocking its cholesterization .
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Cat. No.: HY-174591
Target:  

mRNA

Research Areas:  

Neurological Disease

Human LHX3 mRNA encodes the human LIM homeobox 3 (LHX3) protein, a member of a large proteins family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. LHX3 is a transcription factor that is required for pituitary development and motor neuron specification.
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Cat. No.: HY-133974
CAS No.: 64907-23-9
Synonyms: 7-keto-25-OHC
Target:  

Smo

Research Areas:  

Cancer

7-keto-25-Hydroxycholesterol (7-keto-25-OHC), a oxysterol, is a Smoothened (Smo) activator. 7-keto-25-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo .
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Cat. No.: HY-P75331
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRIPT; cysteine-rich Interactor Of PDZ3; CXXC Repeat Containing Interactor Of PDZ3 domain; Postsynaptic Protein CRIPT; cysteine-rich PDZ-Binding Protein; SSMDF; cysteine-rich Interactor Of PDZ Three; RTS3; HSPC139
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P76290
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRIP2; cysteine-rich Intestinal Protein; cysteine rich Protein 2; LIM domain Protein ESP1/CRP2; CRP2; Protein ESP1; cysteine-rich Protein 2; CRP-2; ESP1; CRIP
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P76291
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRIP2; cysteine-rich Intestinal Protein; cysteine rich Protein 2; LIM domain Protein ESP1/CRP2; CRP2; Protein ESP1; cysteine-rich Protein 2; CRP-2; ESP1; CRIP
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P810375
Synonyms: cysteine rich protein TTG 2, cysteine rich protein TTG2, cysteine-rich protein TTG-2, LIM domain only 2 (rhombotin like 1), LIM domain only 2, LIM domain only protein 2, LMO 2, LMO-2, lmo2, RBTN 2

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P70081
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD2; cysteine-rich With EGF-Like domain Protein 2; CRELD Disulfide Isomerase 2; Protein Disulfide Isomerase CRELD2; cysteine rich With EGF Like domains 2; MGC11256
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76289
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD2; cysteine-rich With EGF-Like domain Protein 2; CRELD Disulfide Isomerase 2; Protein Disulfide Isomerase CRELD2; cysteine rich With EGF Like domains 2; MGC11256
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76288
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRELD2; cysteine-rich With EGF-Like domain Protein 2; CRELD Disulfide Isomerase 2; Protein Disulfide Isomerase CRELD2; cysteine rich With EGF Like domains 2; MGC11256
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P700637
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD2; cysteine-rich With EGF-Like domain Protein 2; CRELD Disulfide Isomerase 2; Protein Disulfide Isomerase CRELD2; cysteine rich With EGF Like domains 2; MGC11256
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75534
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADAM15; A Disintegrin And Metalloproteinase domain 15 (Metargidin); ADAM Metallopeptidase domain 15; Metalloprotease RGD Disintegrin Protein; MDC15; Metargidin; Metalloproteinase-Like, Disintegrin-Like, And cysteine-rich Protein 15; MDC-15; Disintegrin An
Species:  
Human
Source:  
CHO
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Cat. No.: HY-P75533
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADAM15; A Disintegrin And Metalloproteinase domain 15 (Metargidin); ADAM Metallopeptidase domain 15; Metalloprotease RGD Disintegrin Protein; MDC15; Metargidin; Metalloproteinase-Like, Disintegrin-Like, And cysteine-rich Protein 15; MDC-15; Disintegrin An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75564
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADAM15; A Disintegrin And Metalloproteinase domain 15 (Metargidin); ADAM Metallopeptidase domain 15; Metalloprotease RGD Disintegrin Protein; MDC15; Metargidin; Metalloproteinase-Like, Disintegrin-Like, And cysteine-rich Protein 15; MDC-15; Disintegrin An
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P75533A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADAM15; A Disintegrin And Metalloproteinase domain 15 (Metargidin); ADAM Metallopeptidase domain 15; Metalloprotease RGD Disintegrin Protein; MDC15; Metargidin; Metalloproteinase-Like, Disintegrin-Like, And cysteine-rich Protein 15; MDC-15; Disintegrin An
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76285
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD1; cysteine-rich With EGF-Like domain Protein 1; Prev. AVSD2; Atrioventricular Septal Defect 2; cysteine rich With EGF Like domains 1; Protein Disulfide-Isomerase; CIRRIN; JELANS; CRELD Disulfide Isomerase 1; Protein Disulfide Isomerase CRELD1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76287
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD1; cysteine-rich With EGF-Like domain Protein 1; Prev. AVSD2; Atrioventricular Septal Defect 2; cysteine rich With EGF Like domains 1; Protein Disulfide-Isomerase; CIRRIN; JELANS; CRELD Disulfide Isomerase 1; Protein Disulfide Isomerase CRELD1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76286
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRELD1; cysteine-rich With EGF-Like domain Protein 1; Prev. AVSD2; Atrioventricular Septal Defect 2; cysteine rich With EGF Like domains 1; Protein Disulfide-Isomerase; CIRRIN; JELANS; CRELD Disulfide Isomerase 1; Protein Disulfide Isomerase CRELD1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P81528
Synonyms: LMO2; RBTN2, RBTNL1, RHOM2, TTG2; Rhombotin-2; cysteine-rich protein TTG-2; LIM domain only protein 2 (LMO-2); T-cell translocation protein 2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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