4 Results for "

folic acid formation

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "folic acid formation" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-14769
CAS No.: 3432-99-3
Purity:  86.60%
Synonyms: 5,10-Methylenetetrafolate; ANX-510 free acid
Folitixorin (5,10-Methylenetetrafolate; ANX-510 free acid) is a reduced form of Folic acid (HY-16637) and a cofactor of thymidylate synthase . Folitixorin acts as an essential cofactor to promote the formation of a tight ternary complex between thymidylate synthase and FdUMP, thereby enhancing the inhibitory effect of FdUMP on thymidylate synthase. Folitixorin in combination with 5-fluorouracil and αVEGF reduces tumor volume in colorectal tumor models of nude mice. Folitixorin is used in related research on Yoshida sarcoma, P-388 leukemia, and colorectal cancer .
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2
2 Cited Publications
Cat. No.: HY-B0333
CAS No.: 144-82-1
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms .
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Cat. No.: HY-14769A
CAS No.: 133978-75-3
Synonyms: 5,10-Methylenetetrafolate calcium; ANX-510
Target:  

Thymidylate Synthase

Research Areas:  

Cancer

Folitixorin calcium (5,10-Methylenetetrafolate calcium; ANX-510) is a reduced form of Folic acid (HY-16637) and a cofactor of thymidylate synthase . Folitixorin calcium acts as an essential cofactor to promote the formation of a tight ternary complex between thymidylate synthase and FdUMP, thereby enhancing the inhibitory effect of FdUMP on thymidylate synthase. Folitixorin calcium in combination with 5-fluorouracil and αVEGF reduces tumor volume in colorectal tumor models of nude mice. Folitixorin calcium is used in related research on Yoshida sarcoma, P-388 leukemia, and colorectal cancer .
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Cat. No.: HY-14769B
CAS No.: 133978-76-4
Synonyms: 5,10-Methylenetetrafolate sodium; ANX-510 sodium
Target:  

Thymidylate Synthase

Research Areas:  

Cancer

Folitixorin sodium (5,10-Methylenetetrafolate sodium; ANX-510 sodium) is a reduced form of Folic acid (HY-16637) and a cofactor of thymidylate synthase . Folitixorin sodium acts as an essential cofactor to promote the formation of a tight ternary complex between thymidylate synthase and FdUMP, thereby enhancing the inhibitory effect of FdUMP on thymidylate synthase. Folitixorin sodium in combination with 5-fluorouracil and αVEGF reduces tumor volume in colorectal tumor models of nude mice. Folitixorin sodium is used in related research on Yoshida sarcoma, P-388 leukemia, and colorectal cancer .
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