3 Results for "

fosmidomycin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "fosmidomycin" in MCE Product Catalog:

Cat. No.: HY-134914
CAS No.: 66508-53-0
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-112853
CAS No.: 66508-37-0
Purity:  99.72%
Synonyms: FR-31564
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.
loading...
    loading...
Cat. No.: HY-151965
CAS No.: 3037689-82-7
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 18 is an potent antimalarial agent, based on electronic, highly lipophilic and siderophoric properties. Antimalarial agent 18 belongs to acyloxymethyl series, as a fosmidomycin surrogate, which is potent IspC inhibitor against the non-mevalonate isoprenoid biosynthesis pathway. Antimalarial agent 18 inhibits P. falciparum (IC50=50 nM) and A. baumanii (IC50=390 nM) .
loading...
    loading...