31 Results for "

gastritis

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "gastritis" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-B0360
CAS No.: 90098-04-7
Synonyms: OPC12759; Proamipide
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .
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3
3 Cited Publications
Cat. No.: HY-N0366
CAS No.: 128-57-4
Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis .
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2
2 Cited Publications
Cat. No.: HY-14149
CAS No.: 81098-60-4
Purity:  99.87%
Synonyms: R 51619; (±)-Cisaprid
Research Areas:  

Inflammation/Immunology

Cisapride (R 51619) is an orally active, selective 5-HT4 receptor agonist with an EC50 of 140 nM. Cisapride also acts as an hERG potassium channel blocker with an IC50 of 9.4 nM. Cisapride exerts gastrointestinal prokinetic effects by activating 5-HT4 receptors, but it also blocks the hERG potassium channel responsible for the repolarization phase of cardiac action potentials, delaying repolarization and thus prolonging the action potential duration . Cisapride can be used in research related to gastrointestinal dysfunction, gastroesophageal reflux disease, functional dyspepsia, chronic gastritis, gastroparesis, ulcerative colitis and necrotizing enterocolitis .
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2
2 Cited Publications
Cat. No.: HY-14149A
CAS No.: 260779-88-2
Synonyms: R 51619 monohydrate; (±)-Cisaprid monohydrate
Research Areas:  

Inflammation/Immunology

Cisapride (R 51619) monohydrate is an orally active, selective 5-HT4 receptor agonist with an EC50 of 140 nM. Cisapride monohydrate also acts as an hERG potassium channel blocker with an IC50 of 9.4 nM. Cisapride monohydrate exerts gastrointestinal prokinetic effects by activating 5-HT4 receptors, but it also blocks the hERG potassium channel responsible for the repolarization phase of cardiac action potentials, delaying repolarization and thus prolonging the action potential duration . Cisapride monohydrate can be used in research related to gastrointestinal dysfunction, gastroesophageal reflux disease, functional dyspepsia, chronic gastritis, gastroparesis, ulcerative colitis and necrotizing enterocolitis .
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1
1 Cited Publications
Cat. No.: HY-P990209
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .
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1
1 Cited Publications
Cat. No.: HY-N4280
CAS No.: 2445-80-9
7,8-Dimethoxycoumarin is a coumarin compound derived from Artemisia caruifolia with oral activity. 7,8-Dimethoxycoumarin inhibits mitochondrial permeability transition pore and H +/K +-ATPase, and exhibits antioxidant, anti-inflammatory, renoprotective, neuroprotective and gastroprotective effects. 7,8-Dimethoxycoumarin reduces lipid peroxidation (TBARS), increases GSH levels, inhibits myeloperoxidase (MPO) activity, and regulates the expression of inflammatory factors by inhibiting the NF‑κB and MAPK pathways. 7,8-Dimethoxycoumarin ameliorates gastric mucosal injury, alleviates renal tissue lesions and relieves neuropathic pain. 7,8-Dimethoxycoumarin can be used in studies related to acute renal failure, trigeminal neuralgia and gastritis .
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Cat. No.: HY-B0758
CAS No.: 30751-05-4
Target:  

Calcium Channel

Research Areas:  

Inflammation/Immunology

Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties .
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Cat. No.: HY-P99371
CAS No.: 2283348-97-8
Synonyms: AK002; Antolimab

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .
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Cat. No.: HY-N5048
CAS No.: 122965-41-7
Synonyms: 6'-O-Galloyl paeoniflorin
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases .
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Cat. No.: HY-B2191
CAS No.: 6223-35-4
Synonyms: Guaiazulenesulfonate sodium
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
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Cat. No.: HY-B2206
CAS No.: 51-77-4
Target:  

Mucin

Research Areas:  

Inflammation/Immunology

Gefarnate is a agent used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome.
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Cat. No.: HY-B2191R
CAS No.: 6223-35-4
Synonyms: Guaiazulenesulfonate sodium (Standard)
Sodium gualenate (Standard) is the analytical standard of Sodium gualenate. This product is intended for research and analytical applications. Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
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Cat. No.: HY-122762
CAS No.: 27724-96-5
Purity:  99.37%
Synonyms: DV-1006
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Cetraxate hydrochloride (DV-1006), an orally active anti-ulcer agent with mucosal protective effects, can be used for gastric ulcers research . Cetraxate hydrochloride is a potent acrosomal proteinase acrosin inhibitor with a Ki and an IC50 of 0.94 μM and 3.3 μM, respectively .
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Cat. No.: HY-N9451
CAS No.: 84696-15-1
Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo .
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Cat. No.: HY-75424A
CAS No.: 2062-25-1
Target:  

Proton Pump

Research Areas:  

Inflammation/Immunology

2-(Trifluoromethyl)cinnamic acid is a cinnamic acid derivative that inhibits the proton pump (H +/K +-ATPase), thereby reducing gastric acid secretion. 2-(Trifluoromethyl)cinnamic acid also improves delayed gastric emptying and can be used in research on gastric diseases such as acute gastritis and gastric ulcers .
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Cat. No.: HY-B0360R
CAS No.: 90098-04-7
Target:  

COX Reference Standards

Research Areas:  

Inflammation/Immunology Cancer

Rebamipide (Standard) is the analytical standard of Rebamipide. This product is intended for research and analytical applications. Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .
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Cat. No.: HY-B2191A
CAS No.: 116277-75-9
Synonyms: Guaiazulenesulfonate sodium hydrate
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Sodium gualenate hydrate (Guaiazulenesulfonate sodium hydrate) is a derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis .
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Cat. No.: HY-24547
CAS No.: 331649-59-3
Target:  

Phospholipase

Research Areas:  

Infection

HpFabZ-IN-1 (Compound 1) is an inhibitor of the key enzyme FabZ in the Helicobacter pylori fatty acid synthesis pathway, with its IC50 value being 39.8 µM. HpFabZ-IN-1 does not possess antibacterial activity .
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Cat. No.: HY-105507
CAS No.: 132928-46-2
PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis .
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Cat. No.: HY-D3005
NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm). NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast .
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