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Results for "

gastritis

" in MedChemExpress (MCE) Product Catalog:

標的別:	Akt (1) Apoptosis (2) Autophagy (1) Bacterial (3) Calcium Channel (2) COX (2) DNA/RNA Synthesis (1) Drug Derivative (3) ERK (1) Fluorescent Dye (1) Glutathione Peroxidase (1) Interleukin Related (2) JNK (1) Keap1-Nrf2 (1) Leukotriene Receptor (1) Mucin (1) Na+/K+ ATPase (1) NF-κB (3) Nuclear Factor of activated T Cells (NFAT) (1) p38 MAPK (1) PDGFR (1) Phospholipase (1) PI3K (1) Platelet-activating Factor Receptor (PAFR) (1) Proton Pump (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Ser/Thr Protease (1)
研究分野別:	Cancer (4) Cardiovascular Disease (2) Infection (5) Inflammation/Immunology (21) Metabolic Disease (3) Neurological Disease (2)

標的別:

Akt (1)

Apoptosis (2)

Autophagy (1)

Bacterial (3)

Calcium Channel (2)

COX (2)

DNA/RNA Synthesis (1)

Drug Derivative (3)

ERK (1)

Fluorescent Dye (1)

Glutathione Peroxidase (1)

Interleukin Related (2)

JNK (1)

Keap1-Nrf2 (1)

Leukotriene Receptor (1)

Mucin (1)

Na+/K+ ATPase (1)

NF-κB (3)

Nuclear Factor of activated T Cells (NFAT) (1)

p38 MAPK (1)

PDGFR (1)

Phospholipase (1)

PI3K (1)

Platelet-activating Factor Receptor (PAFR) (1)

Proton Pump (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (3)

Ser/Thr Protease (1)

研究分野別:

Cancer (4)

Cardiovascular Disease (2)

Infection (5)

Inflammation/Immunology (21)

Metabolic Disease (3)

Neurological Disease (2)

阻害剤およびアゴニスト

蛍光色素

阻害性抗体

天然物

製品番号	製品名	Target	研究分野	構造式

HY-B0360

Rebamipide Maximum Cited Publications 6 Publications Verification OPC12759; Proamipide	COX	Inflammation/Immunology Cancer
Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .

HY-N0366

Sennoside B 3 Publications Verification	PDGFR	Inflammation/Immunology
Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis .

HY-B0758

Troxipide	Calcium Channel	Inflammation/Immunology
Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties .

HY-P99371

Lirentelimab AK002; Antolimab	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

HY-N5048

Galloylpaeoniflorin 6'-O-Galloyl paeoniflorin	NF-κB ERK JNK Nuclear Factor of activated T Cells (NFAT) Keap1-Nrf2 PI3K Akt Reactive Oxygen Species (ROS) Apoptosis DNA/RNA Synthesis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases .

HY-B2191

Sodium gualenate Guaiazulenesulfonate sodium	Drug Derivative	Inflammation/Immunology
Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.

HY-B2206

Gefarnate	Mucin	Inflammation/Immunology
Gefarnate is a agent used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome.

HY-P990209

Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) 1 Publications Verification	Interleukin Related	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .

HY-B2191R

Sodium gualenate (Standard) Guaiazulenesulfonate sodium (Standard)	Drug Derivative Reference Standards	Inflammation/Immunology
Sodium gualenate (Standard) is the analytical standard of Sodium gualenate. This product is intended for research and analytical applications. Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.

HY-122762

Cetraxate hydrochloride DV-1006	Ser/Thr Protease	Inflammation/Immunology
Cetraxate hydrochloride (DV-1006), an orally active anti-ulcer agent with mucosal protective effects, can be used for gastric ulcers research . Cetraxate hydrochloride is a potent acrosomal proteinase acrosin inhibitor with a K_i and an IC₅₀ of 0.94 μM and 3.3 μM, respectively .

HY-N9451

Ginger extract	NF-κB	Cardiovascular Disease Inflammation/Immunology Cancer
Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo .

HY-75424A

2-(Trifluoromethyl)cinnamic acid	Proton Pump	Inflammation/Immunology
2-(Trifluoromethyl)cinnamic acid is a cinnamic acid derivative that inhibits the proton pump (H ⁺/K ⁺-ATPase), thereby reducing gastric acid secretion. 2-(Trifluoromethyl)cinnamic acid also improves delayed gastric emptying and can be used in research on gastric diseases such as acute gastritis and gastric ulcers .

HY-B0360R

Rebamipide (Standard)	COX Reference Standards	Inflammation/Immunology Cancer
Rebamipide (Standard) is the analytical standard of Rebamipide. This product is intended for research and analytical applications. Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .

HY-B2191A

Sodium gualenate hydrate Guaiazulenesulfonate sodium hydrate	Drug Derivative	Inflammation/Immunology
Sodium gualenate hydrate (Guaiazulenesulfonate sodium hydrate) is a derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis .

HY-24547

HpFabZ-IN-1	Phospholipase	Infection
HpFabZ-IN-1 (Compound 1) is an inhibitor of the key enzyme FabZ in the Helicobacter pylori fatty acid synthesis pathway, with its IC₅₀ value being 39.8 µM. HpFabZ-IN-1 does not possess antibacterial activity .

HY-N4280

7,8-Dimethoxycoumarin 1 Publications Verification	Na+/K+ ATPase Glutathione Peroxidase NF-κB p38 MAPK Interleukin Related	Neurological Disease Metabolic Disease Inflammation/Immunology
7,8-Dimethoxycoumarin is a coumarin compound derived from Artemisia caruifolia with oral activity. 7,8-Dimethoxycoumarin inhibits mitochondrial permeability transition pore and H ⁺/K ⁺-ATPase, and exhibits antioxidant, anti-inflammatory, renoprotective, neuroprotective and gastroprotective effects. 7,8-Dimethoxycoumarin reduces lipid peroxidation (TBARS), increases GSH levels, inhibits myeloperoxidase (MPO) activity, and regulates the expression of inflammatory factors by inhibiting the NF‑κB and MAPK pathways. 7,8-Dimethoxycoumarin ameliorates gastric mucosal injury, alleviates renal tissue lesions and relieves neuropathic pain. 7,8-Dimethoxycoumarin can be used in studies related to acute renal failure, trigeminal neuralgia and gastritis .

HY-D3005

NpCy-4	Fluorescent Dye Autophagy	Inflammation/Immunology
NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm). NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast .

HY-105507

PF-10040	Platelet-activating Factor Receptor (PAFR)	Inflammation/Immunology
PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis .

HY-162149

Urease-IN-12	Bacterial	Infection
Urease-IN-12 (compound 5e) is a competitive urease inhibitor (IC₅₀: 0.35 μM) with the potential to inhibit gastritis and peptic ulcer caused by Helicobacter pylori .

HY-162139

Urease-IN-11	Bacterial	Inflammation/Immunology
Urease-IN-11 (Compound 6e) is a competitive urease inhibitor (IC₅₀)=10.41 µM). Urease-IN-11 can be used to study diseases such as urease-related gastritis and peptic ulcer .

HY-163404

Urease-IN-13	Bacterial	Infection Inflammation/Immunology
Urease-IN-13 (compound d8) is an inhibitor of urease with an IC₅₀ value of 1.21 μM. Urease-IN-13 can be used in the study of infectious gastritis and gastric ulcer .

HY-B0758R

Troxipide (Standard)	Calcium Channel Reference Standards	Inflammation/Immunology
Troxipide (Standard) is the analytical standard of Troxipide. This product is intended for research and analytical applications. Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties .

HY-135288

L-649923	Leukotriene Receptor	Inflammation/Immunology
L-649923 is an orally active CysLT1 antagonist. L-649923 reduced the incidence of gastritis in an animal model of acute gastric mucosal injury. L-649923 can be used in research on diseases such as asthma and gastritis .

NpCy-4	蛍光色素
NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm). NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast .

製品番号	製品名	Target	研究分野	Image

HY-P99371

Lirentelimab AK002; Antolimab	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

HY-P990209

Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) 1 Publications Verification	Interleukin Related	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .

Sennoside B 3 Publications Verification	Quinones Classification of Application Fields Leguminosae Anthraquinones Cassia angustifolia Plants Disease Research Fields Cancer	PDGFR
Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis .

Galloylpaeoniflorin 6'-O-Galloyl paeoniflorin	Structural Classification Paeonia lactiflora Pall. Classification of Application Fields Other Diseases Phenols Polyphenols Plants Paeoniaceae Disease Research Fields Source Classification	NF-κB ERK JNK Nuclear Factor of activated T Cells (NFAT) Keap1-Nrf2 PI3K Akt Reactive Oxygen Species (ROS) Apoptosis DNA/RNA Synthesis
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases .

Ginger extract	Zingiber officinale Roscoe 天然物 Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Source Classification Zingiberaceae	NF-κB
Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo .

7,8-Dimethoxycoumarin 1 Publications Verification	Structural Classification Classification of Application Fields Rutaceae Coumarins Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Citrus reticulata Blanco Source Classification	Na+/K+ ATPase Glutathione Peroxidase NF-κB p38 MAPK Interleukin Related
7,8-Dimethoxycoumarin is a coumarin compound derived from Artemisia caruifolia with oral activity. 7,8-Dimethoxycoumarin inhibits mitochondrial permeability transition pore and H ⁺/K ⁺-ATPase, and exhibits antioxidant, anti-inflammatory, renoprotective, neuroprotective and gastroprotective effects. 7,8-Dimethoxycoumarin reduces lipid peroxidation (TBARS), increases GSH levels, inhibits myeloperoxidase (MPO) activity, and regulates the expression of inflammatory factors by inhibiting the NF‑κB and MAPK pathways. 7,8-Dimethoxycoumarin ameliorates gastric mucosal injury, alleviates renal tissue lesions and relieves neuropathic pain. 7,8-Dimethoxycoumarin can be used in studies related to acute renal failure, trigeminal neuralgia and gastritis .

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