60 Results for "

glucocorticoid corticosteroid

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "glucocorticoid corticosteroid" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-17463
CAS No.: 50-24-8
Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research .
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12
12 Publications Verification
Cat. No.: HY-B1232
CAS No.: 54-36-4
Synonyms: Su-4885
Metyrapone (Su-4885) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushing's syndrome and depression .
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4
4 Cited Publications
Cat. No.: HY-13693
CAS No.: 83919-23-7
Purity:  99.86%
Synonyms: Sch32088
Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo
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2
2 Cited Publications
Cat. No.: HY-B1893
CAS No.: 426-13-1
Research Areas:  

Inflammation/Immunology

Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye .
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2
2 Cited Publications
Cat. No.: HY-B0328
CAS No.: 124-94-7
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory and neuroprotective effects through binding to glucocorticoid receptors. Triamcinolone can relieve several dermatitis, immune diseases and ocular diseases .
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2
2 Cited Publications
Cat. No.: HY-B0248
CAS No.: 638-94-8
Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. Desonide can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis .
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2
2 Cited Publications
Cat. No.: HY-113447
CAS No.: 72-23-1
Purity:  95.24%
11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast .
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1
1 Cited Publications
Cat. No.: HY-B1121
CAS No.: 3385-03-3
Flunisolide is a corticosteroid, which is an orally active glucocorticoid receptor activator with anti-inflammatory activity. Flunisolide can induce eosinophil apoptosis, and is used for the research of asthma or rhinitis, and inflammation .
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1
1 Cited Publications
Cat. No.: HY-B0154
CAS No.: 80474-14-2
Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .
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1
1 Cited Publications
Cat. No.: HY-B0878
CAS No.: 66852-54-8
Synonyms: BMY-30056; CGP-14458; Ulobetasol propionate
Research Areas:  

Inflammation/Immunology

Halobetasol propionate (BMY-30056) is a synthetic glucocorticoid corticosteroid. Halobetasol propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Halobetasol propionate can be used for the study of psoriasis .
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1
1 Cited Publications
Cat. No.: HY-B1616
CAS No.: 25122-57-0
Research Areas:  

Inflammation/Immunology

Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis .
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1
1 Cited Publications
Cat. No.: HY-B0727
CAS No.: 2152-44-5
Synonyms: Betamethasone 17-valerate
Research Areas:  

Inflammation/Immunology

Betamethasone valerate (Betamethasone 17-valerate), the 17-valerate ester of Betamethasone, is a topical corticosteroid with anti-inflammatory activity. Betamethasone valerate is used in the treatment of recurrent aphthous stomatitis. Betamethasone valerate inhibits the binding of the radiolabeled glucocorticoid dexamethasone ( 3H dexamethasone) to human epidermis and mouse skin with IC50s of 5 and 6 nM, respectively .
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1
1 Cited Publications
Cat. No.: HY-U00089
CAS No.: 508-99-6
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
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1
1 Cited Publications
Cat. No.: HY-B1471
CAS No.: 3801-06-7
Target:  

Carbonic Anhydrase

Research Areas:  

Inflammation/Immunology

Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonic anhydrase (CA) with IC50s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research .
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Cat. No.: HY-113114
CAS No.: 53-05-4
Purity:  99.96%
Tetrahydrocortisone is a corticosteroid catalyzed from endogenous glucocorticoids by AKR1D1 (5β-reductase). Its formation is mediated by AKR1D1 and regulated by the glucocorticoid receptor (GR). As one of the final products of glucocorticoid inactivation metabolism, Tetrahydrocortisone participates in the maintenance of glucocorticoid metabolic homeostasis in vivo. Tetrahydrocortisone can be used for mechanistic studies of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes, and also serves as a biomarker for in vivo AKR1D1 activity and glucocorticoid metabolic status .
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Cat. No.: HY-17463R
CAS No.: 50-24-8
Prednisolone (Standard) is the analytical standard of Prednisolone. This product is intended for research and analytical applications. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research .
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Cat. No.: HY-B0154S1
CAS No.: 1093258-28-6
Fluticasone propionate-d5 is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .
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Cat. No.: HY-132269
CAS No.: 338-95-4
Purity:  99.44%
Research Areas:  

Inflammation/Immunology

Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases .
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Cat. No.: HY-106714
CAS No.: 34097-16-0
Purity:  99.93%
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology

Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis .
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Cat. No.: HY-B1383
CAS No.: 79-61-8
Research Areas:  

Inflammation/Immunology

Dichlorisone acetate is a synthetic glucocorticoid corticosteroid used as an anti-inflammatory agent.
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