1. GPCR/G Protein
  2. Glucocorticoid Receptor
  3. Fluorometholone

Fluorometholone 

Cat. No.: HY-B1893 Purity: 99.49%
Handling Instructions

Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye.

For research use only. We do not sell to patients.

Fluorometholone Chemical Structure

Fluorometholone Chemical Structure

CAS No. : 426-13-1

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 105 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 105 In-stock
Estimated Time of Arrival: December 31
Solid
25 mg USD 95 In-stock
Estimated Time of Arrival: December 31
50 mg USD 170 In-stock
Estimated Time of Arrival: December 31
100 mg USD 306 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Fluorometholone

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye[1].

IC50 & Target

glucocorticoid receptor[1]

In Vitro

Fluorometholone (25-100 nM; 12 hours, 24 hours) increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in the conjunctival and corneal epithelial cells through activation of glucocorticoid receptors[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

376.46

Formula

C₂₂H₂₉FO₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (132.82 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6563 mL 13.2816 mL 26.5632 mL
5 mM 0.5313 mL 2.6563 mL 5.3126 mL
10 mM 0.2656 mL 1.3282 mL 2.6563 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.64 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Fluorometholone
Cat. No.:
HY-B1893
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