2 Results for "

glycyl-tRNA synthetase

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "glycyl-tRNA synthetase" in MCE Product Catalog:

Cat. No.: HY-169810
CAS No.: 849658-87-3
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance .
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Cat. No.: HY-P74128
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: GARS1; Charcot-Marie-Tooth Neuropathy 2D; Prev. GARS; Charcot-Marie-Tooth Neuropathy, Neuronal Type, D; Prev. CMT2D; Glycine tRNA Ligase; GlyRS; AP-4-A synthetase; Diadenosine Tetraphosphate synthetase; HMN5A; glycyl-tRNA synthetase; HMND5; Glycine--tRNA
Species:  
Human
Source:  
Sf9 insect cells
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