7 Results for "

hCaSR

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "hCaSR" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P4633
CAS No.: 7432-23-7
γ-Glu-Tyr is an orally active gut microbiota-derived metabolite and a competitive DPP-IV inhibitor with an IC50 of 6.77 mM against hDPP-IV. γ-Glu-Tyr weakly activates hCaSR. γ-Glu-Tyr decreases colonic pro-inflammatory cytokine (IL-6, IL-1β, TNF-α) levels. γ-Glu-Tyr activates the cAMP/PKA signaling pathway and inhibits NF-κB phosphorylation, thereby reducing inflammatory responses. γ-Glu-Tyr can be used for research on type 2 diabetes and ulcerative colitis .
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Cat. No.: HY-P4376A
Target:  

CaSR

Research Areas:  

Others

Gamma-Glu-Abu TFA is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu TFA interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group .
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Cat. No.: HY-179475
CAS No.: 1262781-19-0
Target:  

CaSR

Research Areas:  

Endocrinology

KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC50 of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .
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Cat. No.: HY-P4376
CAS No.: 16869-42-4
Target:  

CaSR

Research Areas:  

Others

Gamma-Glu-Abu is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group .
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Cat. No.: HY-RS01974
Research Areas:  

Others

CASR Human Pre-designed siRNA Set A contains three designed siRNAs for CASR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P4376B
Target:  

CaSR

Research Areas:  

Others

Gamma-Glu-Abu acetate is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu acetate interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group .
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Cat. No.: HY-P79408
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CASR; Parathyroid Ca(2+)-Sensing Receptor 1; Prev. HHC1; Hypocalciuric Hypercalcemia 1; Prev. HHC; Calcium-Sensing Receptor; GPRC2A; HYPOC1; Extracellular Calcium-Sensing Receptor; PCaR1; NSHPT; EIG8; FHH; CaSR; Parathyroid Cell Calcium-Sensing Receptor 1
Species:  
Human
Source:  
HEK293
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